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Showing results 1 - 18 of 18:
Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Compound Intervention: spermidine (4 mM)
median lifespan increased 233.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Compound Intervention: spermidine (1 mM)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Compound Intervention: spermidine (0.2 mM)
mean lifespan increased 15.38% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: bec-1 RNAi knockdown
  • Compound Intervention: spermidine (0.2 mM)
mean lifespan decreased -22.62% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: bec-1 RNAi knockdown
mean lifespan decreased -28.51% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Compound Intervention: spermidine (0.01 mM)
median lifespan increased 25% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Compound Intervention: spermidine (0.1 mM)
median lifespan increased 27.5% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Compound Intervention: spermidine (1 mM)
median lifespan increased 50% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: atg7 loss of function
  • Compound Intervention: spermidine (1 mM)
median lifespan decreased -12.5% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: atg7 loss of function
  • Compound Intervention: spermidine (0.1 mM)
median lifespan decreased -12.5% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: atg7 loss of function
  • Compound Intervention: spermidine (0.01 mM)
median lifespan decreased -12.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Compound Intervention: spermidine (4 mM)
median lifespan increased 100% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: iki3 deletion / null
  • Gene Intervention: sas3 deletion / null
  • Compound Intervention: spermidine (4 mM)
median lifespan increased 46.67% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: iki3 deletion / null
  • Gene Intervention: sas3 deletion / null
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: spe1 deletion / null
median lifespan decreased -50% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: spe1 deletion / null
  • Compound Intervention: spermidine (0.1 mM)
median lifespan decreased (significant)
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Lifespan Observation Mus musculus (Jc1:ICR) male
  • Environment Intervention: High polyamine diet
median lifespan increased 23.81% (significant)
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Lifespan Observation Mus musculus (Jc1:ICR) male
  • Environment Intervention: Low polyamine diet
median lifespan increased 3.81%
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