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Showing results 1 - 100 of 125:
Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: QPT1 deletion / null
mean lifespan increased 10.24%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
median lifespan increased 63.64% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
  • Environment Intervention: dietary restriction
median lifespan increased 109.09% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-1 (ad427) loss of function
mean lifespan increased 33.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316)
  • Gene Intervention: CDC25 non-null recessive
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-1 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-15 unknown
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: unc-2 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-20 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-24 (e138) non-null recessive
mean lifespan increased 1.05%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-25 (e265) loss of function
mean lifespan increased 5.07%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-26 (e156) non-null recessive
mean lifespan increased 44.22% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-29 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-30 (e318) non-null recessive
mean lifespan decreased -21.76% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-4 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-46 (e177) non-null recessive
median lifespan decreased -0.46%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-47 (e367) non-null recessive
mean lifespan decreased -5.09%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-49 (e382) non-null recessive
lifespan increased 6.45%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-54 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-6 unknown
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: unc-7 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-78 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-79 (e1068) non-null recessive
mean lifespan increased 11.06% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-80 (qm2) non-null recessive
mean lifespan increased 6.53%
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Lifespan Observation Drosophila melanogaster (Canton-S)
  • Gene Intervention: RPD3 non-null recessive
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (Canton-S)
  • Gene Intervention: RPD3 non-null recessive
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
median lifespan increased 81.82% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
median lifespan increased 53.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG2 deletion / null
  • Environment Intervention: dietary restriction
median lifespan increased 66.67% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG2 deletion / null
median lifespan decreased -26.67% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-1 (e2343) loss of function
mean lifespan increased 10.65% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-5 (ad464) loss of function
mean lifespan decreased -6.48% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-7 (ad450) loss of function
mean lifespan decreased -35.19% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad453) loss of function
mean lifespan increased 35.9% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad465) loss of function
mean lifespan increased 28.72% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad1113) loss of function
mean lifespan increased 45.64% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad1116) loss of function
mean lifespan increased 56.92% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad820sd) loss of function
mean lifespan increased 37.95% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad1110) loss of function
mean lifespan increased 14.87% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-3 (ad426) loss of function
mean lifespan increased 10.55% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-6 (ad792) loss of function
mean lifespan increased 36.18% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-6 (ad467) loss of function
mean lifespan increased 36.68% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-6 (ad601) loss of function
mean lifespan increased 14.57% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-6 (ad997) loss of function
mean lifespan increased 18.59% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-10 (ad606) loss of function
mean lifespan increased 8.04%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-13 (ad522) loss of function
mean lifespan increased 30.65% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (m26) loss of function
mean lifespan decreased -8.65% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (m26) loss of function
  • Gene Intervention: clk-1 (e2519) loss of function
mean lifespan increased 12.98% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: clk-1 (e2519) loss of function
mean lifespan increased 20.19% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (m26) loss of function
mean lifespan decreased -11.68% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad465) loss of function
mean lifespan increased 33.5% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (m26) loss of function
  • Gene Intervention: eat-2 (ad465) loss of function
mean lifespan increased 19.8% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-24 (e448) loss of function
mean lifespan increased 0.53%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-24 (e927) loss of function
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-24 (e1172) loss of function
mean lifespan increased 3.68%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-25 (e591) loss of function
mean lifespan increased 1.84%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-25 (e891) loss of function
mean lifespan increased 3.69%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-25 (e156) non-null recessive
mean lifespan increased 26.13% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-26 (e345) non-null recessive
mean lifespan increased 46.73% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-26 (e1196) non-null recessive
mean lifespan increased 37.19% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-26 (m26) non-null recessive
mean lifespan increased 34.67% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-30 (e596) non-null recessive
mean lifespan decreased -8.54% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-30 (e191) non-null recessive
mean lifespan increased 0.5%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-79 (e1030) non-null recessive
mean lifespan decreased -4.02%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-79 (qm12) non-null recessive
mean lifespan decreased -1.01%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-79 (qm14) non-null recessive
mean lifespan increased 10.05% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-80 (e1272) non-null recessive
mean lifespan increased 10.55% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-80 (qm3) non-null recessive
mean lifespan increased 1.01%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-80 (qm9) non-null recessive
mean lifespan decreased -2.01%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad465) loss of function
mean lifespan increased 20.09% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad465) loss of function
  • Gene Intervention: daf-2 (e1370) loss of function
mean lifespan increased 89.95% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1370) loss of function
mean lifespan increased 55.71% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad465) loss of function
  • Gene Intervention: clk-1 (e2519) loss of function
mean lifespan increased 39.59% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-2 (ad465) loss of function
mean lifespan increased 33.5% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: clk-1 (e2519) loss of function
mean lifespan increased 27.41% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-18 (ad820sd) loss of function
mean lifespan increased 37.95% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-18 (ad1110) loss of function
mean lifespan increased 14.87% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Sir2 over-expression
lifespan increased 57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 73.95% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
mean lifespan increased 103.36% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 97.48% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 139.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 142.86% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
  • Environment Intervention: dietary restriction
mean lifespan increased 157.98% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
  • Environment Intervention: dietary restriction
  • Environment Intervention: dietary restriction
mean lifespan increased 78.99% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 59.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HDA1 deletion / null
mean lifespan decreased -7.52%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HDA1 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 106.77% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 83.46% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HDA1 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 106.77% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
  • Environment Intervention: dietary restriction
mean lifespan increased 98.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HDA1 deletion / null
  • Environment Intervention: dietary restriction
  • Environment Intervention: dietary restriction
mean lifespan increased 102.26% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 32% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -46.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan decreased -27.2% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 102.29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -37.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan decreased -16.03% (significant)
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Lifespan Observation Mus musculus (wild)
  • Environment Intervention: Caloric restriction
mean lifespan decreased -2.01% (significant)
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Lifespan Observation Mus musculus (wild)
  • Environment Intervention: Caloric restriction
max lifespan increased 14.11% (significant)
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