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Showing results 1 - 100 of 1617:
Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-28 (sa191) non-null semi-dominant
mean lifespan increased 13.04% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (m26) non-null semi-dominant
mean lifespan decreased -13.04% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (m26) non-null semi-dominant
  • Gene Intervention: daf-28 (sa191) non-null semi-dominant
mean lifespan decreased -32.37% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-12 (m20) non-null semi-dominant
  • Gene Intervention: daf-28 (sa191) non-null semi-dominant
mean lifespan decreased -2.9%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-12 (m20) non-null semi-dominant
mean lifespan increased 4.83%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6) loss of function
mean lifespan decreased -6.4% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6) loss of function
max lifespan increased 23.56% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh8) loss of function
mean lifespan decreased -8.8% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh10) loss of function
mean lifespan decreased -9.2% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (rh50) loss of function
mean lifespan decreased -18% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (e1406) loss of function
mean lifespan increased 6.4%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-12 (rh61rh411) loss of function
mean lifespan decreased -11.2% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (mgDf90) loss of function
mean lifespan decreased -13.6% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1368) loss of function
mean lifespan increased 47.2% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1370) loss of function
mean lifespan increased 73.6% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (rh50;e1368) loss of function
mean lifespan increased 19.6% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (rh50;e1370) loss of function
mean lifespan increased 36.4% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (e1406 rh61rh411) loss of function
mean lifespan decreased -3.6%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (rh50) loss of function
mean lifespan decreased -20.88% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1368) loss of function
mean lifespan increased 60.99% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1370) loss of function
mean lifespan increased 57.69% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (rh50;e1368) loss of function
mean lifespan increased 36.81% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: germ cell ablation
  • Environment Intervention: somatic gonad ablation
mean lifespan decreased -14.81% (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
  • Environment Intervention: germ cell ablation
mean lifespan increased 47.69% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (rh50 ) loss of function
  • Environment Intervention: germ cell ablation
  • Environment Intervention: somatic gonad ablation
mean lifespan decreased -14.36% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (rh50 ) loss of function
  • Environment Intervention: germ cell ablation
mean lifespan decreased -9.9%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6;dhEx24) loss of function
  • Environment Intervention: germ cell ablation
  • Environment Intervention: somatic gonad ablation
mean lifespan increased 8.12% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6;dhEx24) loss of function
  • Environment Intervention: germ cell ablation
mean lifespan increased 31.98% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6) loss of function
  • Environment Intervention: germ cell ablation
  • Environment Intervention: somatic gonad ablation
mean lifespan increased 17.92%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6) loss of function
  • Environment Intervention: germ cell ablation
mean lifespan decreased -5.19%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6) loss of function
max lifespan increased 23.56% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh8) loss of function
max lifespan increased 20.69% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh10) loss of function
max lifespan increased 17.82% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (e1406) loss of function
max lifespan increased 52.3% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (rh50 ) loss of function
max lifespan decreased -5.17%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-12 (rh61rh411) loss of function
max lifespan increased 9.2% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (mgDf90) loss of function
max lifespan decreased -8.05%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (e1406 rh61rh411) loss of function
max lifespan increased 6.32% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (e1406 mgDf50) loss of function
max lifespan increased 60.92% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1368) loss of function
max lifespan increased 63.79% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1370) loss of function
max lifespan increased 72.41% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (rh50;e1368) loss of function
max lifespan increased 33.62% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (rh50;e1370) loss of function
max lifespan increased 55.17% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (rh50 ) loss of function
max lifespan decreased -7.06% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1368) loss of function
max lifespan increased 64.71% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1370) loss of function
max lifespan increased 87.45% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (rh50;e1368) loss of function
max lifespan increased 58.82% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (rh50;e1370) loss of function
max lifespan increased 176.47% (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
max lifespan decreased -3.23%
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Lifespan Observation Caenorhabditis elegans (N2)
max lifespan increased 67.1% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6;dhEx24) normal
  • Environment Intervention: somatic gonad ablation
  • Environment Intervention: germ cell ablation
max lifespan increased 19.05% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6;dhEx24) normal
  • Environment Intervention: germ cell ablation
max lifespan increased 33.33% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6) normal
max lifespan increased 11.11%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (dh6) normal
max lifespan decreased -10%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-9 (e1406 rh61rh411) loss of function
mean lifespan decreased -3.6%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: des-2 (bs29) loss of function
  • Gene Intervention: des-2 (bs30) normal
lifespan increased 60% (significant)
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Lifespan Observation Drosophila melanogaster (DJ-1βA286)
  • Gene Intervention: dj-1beta loss of function
mean lifespan decreased -24% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: dkf-2 deletion / null
mean lifespan increased 30.77% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: dkf-2 deletion / null
max lifespan increased 18.75% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: dlk-1 loss of function
max lifespan increased 30% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: DLP loss of function
mean lifespan increased 20% (significant)
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Lifespan Observation Saccharomyces cerevisiae (7585-2-2)
  • Gene Intervention: dna2 (dna2-1) loss of function
mean lifespan decreased -69.49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (7585-2-2)
  • Gene Intervention: dna2 (dna2-2 ) loss of function
mean lifespan decreased -69.11% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SS111)
  • Gene Intervention: dna2-2 (dna2-20) loss of function
mean lifespan decreased -83.88% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: dna2-2 (dna2) loss of function
mean lifespan decreased -17.47% (significant)
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Lifespan Observation Saccharomyces cerevisiae ((W303))
  • Gene Intervention: dna2 (dna2-2) loss of function
mean lifespan decreased -69.96% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303)
  • Gene Intervention: sgs1 loss of function
lifespan decreased -39.51% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303)
  • Gene Intervention: sgs1 loss of function
  • Gene Intervention: dna2 (dna2-2) loss of function
mean lifespan decreased -86.83% (significant)
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Lifespan Observation Saccharomyces cerevisiae (7585-2-2)
  • Gene Intervention: fob1 loss of function
mean lifespan increased 43.95% (significant)
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Lifespan Observation Saccharomyces cerevisiae (7585-2-2)
  • Gene Intervention: fob1 loss of function
  • Gene Intervention: dna2 (dna2-2) loss of function
mean lifespan decreased -50.73% (significant)
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Lifespan Observation Saccharomyces cerevisiae (7585-2-2)
  • Gene Intervention: dna2 (dna2-1) loss of function
  • Gene Intervention: sir2 over-expression
mean lifespan decreased -69.11% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SS111)
  • Gene Intervention: pol1 (pol1-14) loss of function
mean lifespan decreased -56.69% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SS111)
  • Gene Intervention: pol1 (pol1-17) loss of function
mean lifespan decreased -20.15% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SS111)
  • Gene Intervention: rad27 ( ) loss of function
mean lifespan decreased -56.31% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SS111)
  • Gene Intervention: ctf4 ( ) loss of function
mean lifespan decreased -75.67% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-18 (ad820sd) loss of function
mean lifespan increased 37.95% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-18 (ad1110) loss of function
mean lifespan increased 14.87% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: egl-4 (ks61) loss of function
mean lifespan increased 54.48% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (m26) loss of function
mean lifespan increased 6.9% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: egl-4 (ks60) loss of function
mean lifespan increased 48.28% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: nuo-1 loss of function
mean lifespan increased 24.37% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: atp-2 loss of function
mean lifespan increased 14.29% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-11 (pkIs539) over-expression
mean lifespan increased 45.52% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-11 (pkIs540) over-expression
mean lifespan increased 30.29% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gap-9 (pkIs531) over-expression
mean lifespan increased 10.86% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-1 (pk15) loss of function
mean lifespan increased 7.46% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-2 (pk16) loss of function
mean lifespan decreased -29.1% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-3 (pk35) loss of function
mean lifespan decreased -14.93% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-4 (pk381) loss of function
mean lifespan increased 5.22%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-5 (pk376) loss of function
mean lifespan increased 5.97% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-6 (pk480) loss of function
mean lifespan decreased -10.45% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-7 (pk610) loss of function
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-8 (pk345) loss of function
mean lifespan decreased -20.15% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-9 (pk438) loss of function
mean lifespan increased 30.6% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-10 (pk362) loss of function
mean lifespan decreased -17.91% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-11 (pk349) loss of function
mean lifespan decreased -4.48%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-12 (pk322te) loss of function
mean lifespan decreased -1.49%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-13 (pk1270) loss of function
mean lifespan decreased -3.73%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-14 (pk347) loss of function
mean lifespan increased 2.24%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-15 (pk477) loss of function
mean lifespan decreased -0.75%
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