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Showing results 1 - 100 of 1785:
Lifespan Observation Saccharomyces cerevisiae (W303-1A) mata
  • Gene Intervention: ADA1 deletion / null
mean lifespan decreased -86.53% (significant)
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Lifespan Observation Caenorhabditis elegans (Bristol N2) hermaphrodite
  • Gene Intervention: osm-3 ((n1540)) non-null recessive
mean lifespan increased 31.91% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: osm-5 (p802) unknown
mean lifespan increased 121.28% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: osm-6 (p811) unknown
mean lifespan increased 56.38% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: ovo non-null dominant
lifespan increased (significant)
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Lifespan Observation Mus musculus (129 SvEv)
  • Gene Intervention: p66shc (heterzygous) deletion / null
median lifespan increased 7.1% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: PDE2 deletion / null
mean lifespan decreased -25.69% (significant)
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Lifespan Observation Caenorhabditis elegans (Bristol N2)
  • Gene Intervention: pdk-1 (sa680) non-null recessive
mean lifespan increased 58.82% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: petite
mean lifespan increased 31.88% (significant)
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Lifespan Observation Saccharomyces cerevisiae (S150-2B)
  • Gene Intervention: PHB1 deletion / null
lifespan decreased (significant)
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Lifespan Observation Saccharomyces cerevisiae (S150-2B)
  • Gene Intervention: PHB2 deletion / null
lifespan decreased (significant)
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Lifespan Observation Mus musculus ((C3H/HeJ x DW/J)F1)
  • Gene Intervention: Pit1 non-null recessive
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: QPT1 deletion / null
mean lifespan increased 10.24%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: rad-8 non-null recessive
mean lifespan increased 33.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD1 deletion / null
mean lifespan decreased -5%
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD26 deletion / null
mean lifespan decreased -4.09%
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD51 deletion / null
lifespan decreased -43.48% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD52 deletion / null
mean lifespan decreased -69.79% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD7 deletion / null
mean lifespan increased 0.45%
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Lifespan Observation Saccharomyces cerevisiae (DBY747)
  • Gene Intervention: RAD9 deletion / null
mean lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303-1A)
  • Gene Intervention: RAD9 deletion / null
mean lifespan decreased -22.82% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SP1) mata
  • Gene Intervention: RAS1 deletion / null
mean lifespan increased 23.26% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SP1) mata
  • Gene Intervention: RAS1 over-expression
mean lifespan decreased -1.11%
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Lifespan Observation Saccharomyces cerevisiae (SP1) mata
  • Gene Intervention: RAS2 over-expression
lifespan increased 42.94% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303-1A) mata
  • Gene Intervention: RIF1 deletion / null
median lifespan decreased -29.26% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YSK663) matalpha
  • Gene Intervention: RPD3 deletion / null
median lifespan increased 40.91% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9)
  • Gene Intervention: RTG2 deletion / null
  • Environment Intervention: petite
lifespan decreased -6.84%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
median lifespan increased 63.64% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
  • Environment Intervention: dietary restriction
median lifespan increased 109.09% (significant)
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Lifespan Observation Saccharomyces cerevisiae (DBY746)
  • Gene Intervention: SCH9 (mTn) non-null recessive
mean lifespan increased 33.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W3031-A) mata
  • Gene Intervention: SGS1 deletion / null
mean lifespan decreased -61.22% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YB332) mata
  • Gene Intervention: NMT1 (451D) loss of function
mean lifespan decreased -47.27% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YB332) mata
  • Gene Intervention: SIP1 deletion / null
mean lifespan decreased -18% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YB332) mata
  • Gene Intervention: SIP2 deletion / null
mean lifespan decreased -51.61% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: sir-2.1 (geEx1) over-expression
mean lifespan increased 14.21% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 34.68% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 )
  • Gene Intervention: SIR3 deletion / null
lifespan decreased -15.89% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR4 deletion / null
lifespan decreased -12.15% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-1 (ad427) loss of function
mean lifespan increased 33.33% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) male
  • Gene Intervention: SOD1 over-expression
lifespan increased 48.11% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SOD1 over-expression
  • Gene Intervention: CTT1 over-expression
lifespan decreased -2%
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Lifespan Observation Drosophila melanogaster male
  • Gene Intervention: SOD1 (human SOD1 driven by D42-GAL4) over-expression
mean lifespan increased 41.24% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSODX1) over-expression
mean lifespan increased 31.44% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: spe-10 (hc104) unknown
mean lifespan increased 26.16% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: CAT over-expression
  • Gene Intervention: SOD1 over-expression
mean lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: STE12 deletion / null
mean lifespan increased 5.77%
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: STE4 deletion / null
mean lifespan increased 1.92%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1370) unknown
mean lifespan increased 32.35% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (sa189) unknown
mean lifespan increased 133.33% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (sa193) unknown
mean lifespan increased 66.67% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BKy1-14c)
  • Gene Intervention: SUN4 deletion / null
lifespan decreased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: tax-2 (p671) unknown
mean lifespan increased 6.91%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: tax-4 (p678) unknown
mean lifespan increased 94.68% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: tkr-1 (Ex) over-expression
mean lifespan increased 91.02% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316)
  • Gene Intervention: CDC25 non-null recessive
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-1 unknown
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Lifespan Observation Caenorhabditis elegans (N2) male
  • Gene Intervention: unc-13 non-null recessive
median lifespan increased 76.78% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-15 unknown
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: unc-2 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-20 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-24 (e138) non-null recessive
mean lifespan increased 1.05%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-25 (e265) loss of function
mean lifespan increased 5.07%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-26 (e156) non-null recessive
mean lifespan increased 44.22% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-29 unknown
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Lifespan Observation Saccharomyces cerevisiae (W3031-A)
  • Gene Intervention: CDC6 non-null recessive
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-30 (e318) non-null recessive
mean lifespan decreased -21.76% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-32 (e189) unknown
median lifespan increased 4.12%
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Lifespan Observation Caenorhabditis elegans (N2) male
  • Gene Intervention: unc-32 (e189) unknown
median lifespan increased 58.29% (significant)
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Lifespan Observation Caenorhabditis elegans (Bristol N2)
  • Gene Intervention: unc-35 non-null recessive
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-4 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-46 (e177) non-null recessive
median lifespan decreased -0.46%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-47 (e367) non-null recessive
mean lifespan decreased -5.09%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-49 (e382) non-null recessive
lifespan increased 6.45%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-54 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-6 unknown
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Lifespan Observation Caenorhabditis elegans (Bristol N2)
  • Gene Intervention: Ceinsulin-1 RNAi knockdown
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: unc-7 unknown
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Lifespan Observation Caenorhabditis elegans
  • Gene Intervention: unc-76 non-null recessive
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-78 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-79 (e1068) non-null recessive
mean lifespan increased 11.06% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-80 (qm2) non-null recessive
mean lifespan increased 6.53%
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Lifespan Observation Mus musculus (FVB)
  • Gene Intervention: Plau over-expression
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: SIR4 deletion / null
median lifespan decreased -10.53% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-11 (e1810) unknown
mean lifespan increased 45.21% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303)
  • Gene Intervention: ZDS1 deletion / null
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303)
  • Gene Intervention: ZDS2 deletion / null
lifespan decreased (significant)
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Lifespan Observation Caenorhabditis elegans (Bristol N2)
  • Gene Intervention: age-1 non-null recessive
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (Bristol N2)
  • Gene Intervention: age-1 non-null recessive
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (Bristol N2)
  • Gene Intervention: age-1 non-null recessive
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-13 (e1805) unknown
mean lifespan increased 32.98% (significant)
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Lifespan Observation Mus musculus (Mixed genetic background)
  • Gene Intervention: Terc deletion / null
lifespan decreased (significant)
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Lifespan Observation Mus musculus (C57BL/6J)
  • Gene Intervention: MsrA deletion / null
lifespan decreased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-2 (p801) unknown
mean lifespan increased 42.55% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: fer-15 (b26) non-null recessive
median lifespan decreased -11.76% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: PCMT over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: PCMT over-expression
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Lifespan Observation Caenorhabditis elegans (Bristol N2)
  • Gene Intervention: mes-1 non-null recessive
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) female
  • Gene Intervention: fem-3 (e1996) unknown
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Lifespan Observation Caenorhabditis elegans (Bristol N2)
  • Gene Intervention: fog-1 non-null recessive
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Lifespan Observation Caenorhabditis elegans (Bristol N2)
  • Gene Intervention: fog-3 non-null recessive
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