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Showing results 1 - 100 of 1332:
Lifespan Observation Caenorhabditis elegans (N2) male
  • Gene Intervention: unc-13 (e51) unknown
  • Gene Intervention: fog-2 (q71) unknown
median lifespan increased 103.55% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) female
  • Gene Intervention: unc-13 (e51) unknown
  • Gene Intervention: fog-2 (q71) unknown
median lifespan increased 1.55%
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Lifespan Observation Caenorhabditis elegans (N2) female
  • Gene Intervention: fog-2 (q71) unknown
median lifespan decreased -23.2% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) female
  • Gene Intervention: fog-2 (q71) unknown
median lifespan increased 9%
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Lifespan Observation Mus musculus (C57BL/6) male
  • Gene Intervention: Prkar2b deletion / null
median lifespan increased 13.69% (significant)
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Lifespan Observation Mus musculus (C57BL/6) female
  • Gene Intervention: Prkar2b deletion / null
median lifespan decreased -2.41%
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Lifespan Observation Saccharomyces cerevisiae (BY4743) diploid
  • Environment Intervention: Dietary restriction
median lifespan increased 380% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Environment Intervention: Dietary restriction
median lifespan increased 400% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AT) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 340% (significant)
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Lifespan Observation Saccharomyces cerevisiae (DBY746) mata
  • Environment Intervention: Dietary restriction
median lifespan increased 340% (significant)
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Lifespan Observation Saccharomyces cerevisiae (DBY746) mata
  • Environment Intervention: pH 6 buffering
median lifespan increased 100% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AT) matalpha
  • Environment Intervention: pH 6 buffering
median lifespan increased 340% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) matalpha
  • Environment Intervention: pH 6 buffering
median lifespan increased 450% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Environment Intervention: pH 6 buffering
median lifespan increased 200% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Environment Intervention: pH 6 buffering
median lifespan increased 500% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Environment Intervention: Transfer to water
median lifespan increased 400% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Environment Intervention: Transfer to water
median lifespan increased 400% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 400% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Compound Intervention: acetic acid (as needed to maintain 10 mM in culture)
  • Environment Intervention: Transfer to water
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Environment Intervention: Transfer to water
median lifespan increased 500% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 500% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Compound Intervention: acetic acid (as needed to maintain 10 mM in culture)
  • Environment Intervention: Dietary restriction
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Compound Intervention: methanol (200 millimolar)
  • Environment Intervention: Transfer to water
median lifespan increased 500% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Compound Intervention: ethanol (200 millimolar)
  • Environment Intervention: Transfer to water
median lifespan increased 100% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Compound Intervention: ethanol (200 millimolar)
  • Environment Intervention: Transfer to water
median lifespan increased 40% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Compound Intervention: ethanol (200 millimolar)
  • Environment Intervention: Transfer to water
  • Environment Intervention: pH 6 buffer
median lifespan increased 380% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4743) matalpha
  • Environment Intervention: Transfer to water
  • Environment Intervention: pH 6 buffer
median lifespan increased 380% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction
median lifespan increased 66.67% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: hsf-1 (sy441) non-null recessive
  • Environment Intervention: Dietary restriction
median lifespan decreased -12.5% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: hsf-1 (sy441) non-null recessive
median lifespan decreased -12.5% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (mu86) non-null recessive
median lifespan decreased -16.67% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (mu86) non-null recessive
  • Environment Intervention: Dietary restriction
median lifespan increased 16.67% (significant)
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Lifespan Observation Caenorhabditis elegans (Q35YFP) hermaphrodite
  • Gene Intervention: hsf-1 RNAi knockdown
  • Environment Intervention: Dietary restriction
median lifespan decreased -53.85% (significant)
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Lifespan Observation Caenorhabditis elegans (Q35YFP) hermaphrodite
  • Gene Intervention: hsf-1 RNAi knockdown
median lifespan decreased -53.85% (significant)
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Lifespan Observation Caenorhabditis elegans (Q35YFP) hermaphrodite
  • Environment Intervention: Dietary restriction
median lifespan increased 50% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-3 (p801) unknown
  • Environment Intervention: Dietary restriction
median lifespan increased 139.13% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction
median lifespan increased 60.87% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-3 (p801) unknown
median lifespan increased 47.83% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-11 (e1810) unknown
median lifespan increased 47.83% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-11 (e1810) unknown
  • Environment Intervention: Dietary restriction
median lifespan increased 160.87% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-10 (e1387) unknown
  • Environment Intervention: Dietary restriction
median lifespan increased 139.13% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-10 (e1387) unknown
median lifespan increased 47.83% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: osm-3 (p802) unknown
median lifespan increased 47.83% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: osm-3 (p802) unknown
  • Environment Intervention: Dietary restriction
median lifespan increased 165.22% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: tax-4 (p678) unknown
  • Environment Intervention: Dietary restriction
median lifespan increased 165.22% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: tax-4 (p678) unknown
median lifespan increased 60.87% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction
mean lifespan increased 59.32% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction
mean lifespan increased 63.56% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction
mean lifespan increased 61.44% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction
mean lifespan increased 49.58% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction
mean lifespan increased 69.76% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction (transient)
mean lifespan increased 19.02% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction (transient)
mean lifespan increased 27.48% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction (transient)
mean lifespan increased 60.81% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction (transient)
  • Environment Intervention: OP50 supernatant
median lifespan increased 39.13% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction (transient)
median lifespan increased 69.57% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction (transient)
median lifespan increased 72.73% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Environment Intervention: Dietary restriction (transient)
  • Environment Intervention: Agar barrier
median lifespan increased 36.36% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Compound Intervention: Glucose (20%)
median lifespan decreased -33.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Compound Intervention: Glucose (10%)
median lifespan decreased -33.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 66.67% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 500% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Increased amino acids
median lifespan increased 185.71% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
median lifespan decreased -14.29%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
median lifespan decreased -14.29%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 128.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 328.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AR) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 160% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AR) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 160% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Environment Intervention: Dietary restriction
median lifespan increased 140% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Environment Intervention: Dietary restriction
median lifespan increased 140% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Compound Intervention: Sorbitol (18%)
median lifespan increased 187.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Compound Intervention: Sodium chloride (300 millimolar)
median lifespan increased 175% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 128.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 328.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AR) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 160% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AR) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 160% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 140% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 140% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: HST1 deletion / null
median lifespan increased 12.5%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: HST1 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 275% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 275% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: HST2 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 275% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: HST2 deletion / null
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: HST3 deletion / null
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: HST4 deletion / null
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: HST4 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 328.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: HST3 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 328.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: HST1 deletion / null
  • Gene Intervention: HST2 deletion / null
  • Gene Intervention: HST3 deletion / null
  • Gene Intervention: HST4 deletion / null
median lifespan decreased -14.29%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
median lifespan increased 257.14% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: HST1 deletion / null
  • Gene Intervention: HST2 deletion / null
  • Gene Intervention: HST3 deletion / null
  • Gene Intervention: HST4 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 257.14% (significant)
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Lifespan Observation Rattus norvegicus (Sprague-Dawley) male
  • Compound Intervention: Marine collagen peptides prepared from chum salmon (Oncorhynchus (2.25%)
mean lifespan increased 8.94% (significant)
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Lifespan Observation Rattus norvegicus (Sprague-Dawley) male
  • Compound Intervention: Marine collagen peptides prepared from chum salmon (Oncorhynchus (4.5%)
mean lifespan increased 8.62% (significant)
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Lifespan Observation Rattus norvegicus (Sprague-Dawley) male
  • Compound Intervention: Marine collagen peptides prepared from chum salmon (Oncorhynchus (9%)
mean lifespan increased 12.02% (significant)
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Lifespan Observation Rattus norvegicus (Sprague-Dawley) female
  • Compound Intervention: Marine collagen peptides prepared from chum salmon (Oncorhynchus (9%)
mean lifespan increased 10.02% (significant)
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Lifespan Observation Rattus norvegicus (Sprague-Dawley) female
  • Compound Intervention: Marine collagen peptides prepared from chum salmon (Oncorhynchus (4.5%)
mean lifespan increased 7.74% (significant)
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Lifespan Observation Rattus norvegicus (Sprague-Dawley) female
  • Compound Intervention: Marine collagen peptides prepared from chum salmon (Oncorhynchus (2.25%)
mean lifespan increased 10.14% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-12 (m20) unknown
  • Gene Intervention: daf-2 (m577) unknown
median lifespan decreased -10% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-12 (m20) unknown
  • Gene Intervention: daf-2 (sa193) unknown
median lifespan increased 11.25% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-12 (m20) unknown
  • Gene Intervention: daf-2 (sa193) unknown
median lifespan increased 2.5%
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