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Showing results 1 - 100 of 298:
Lifespan Observation Drosophila melanogaster
  • Gene Intervention: ovo non-null dominant
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (w1118) male
  • Gene Intervention: SOD1 over-expression
lifespan increased 48.11% (significant)
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Lifespan Observation Drosophila melanogaster male
  • Gene Intervention: SOD1 (human SOD1 driven by D42-GAL4) over-expression
mean lifespan increased 41.24% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSODX1) over-expression
mean lifespan increased 31.44% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: CAT over-expression
  • Gene Intervention: SOD1 over-expression
mean lifespan increased 30% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: PCMT over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: PCMT over-expression
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: chico non-null recessive
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: chico non-null recessive
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: MSRA over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (Canton-S)
  • Gene Intervention: RPD3 non-null recessive
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (Canton-S)
  • Gene Intervention: RPD3 non-null recessive
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: DPOSH over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: CAT (2) over-expression
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Lifespan Observation Drosophila melanogaster (PdL x rtTA; Oregon-R x rtTA)
  • Gene Intervention: VhaSFD over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (PdL x rtTA; Oregon-R x rtTA)
  • Gene Intervention: Sug over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (PdL x rtTA; Oregon-R x rtTA)
  • Gene Intervention: Rdh over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (PdL x rtTA; Oregon-R x rtTA)
  • Gene Intervention: Cct1 over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (PdL x rtTA; Oregon-R x rtTA)
  • Gene Intervention: Fwd over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (PdL x rtTA; Oregon-R x rtTA)
  • Gene Intervention: cher over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (Canton-S, cn bw)
  • Gene Intervention: EcR non-null recessive
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster (Samarkand)
  • Gene Intervention: DTS-3 non-null recessive
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: beach1 deletion / null
lifespan decreased (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Atg7 deletion / null
lifespan increased 33% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Atg8a over-expression
lifespan increased 56% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: bchs deletion / null
lifespan increased 42% (significant)
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Lifespan Observation Drosophila melanogaster (DJ-1α)
  • Gene Intervention: DJ-1alpha RNAi knockdown
lifespan decreased -55.26% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Dnmt2 over-expression
lifespan increased 35% (significant)
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Lifespan Observation Drosophila melanogaster (rrf-3(pk1426))
  • Gene Intervention: dor RNAi knockdown
lifespan increased 70% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Ef1alpha48D over-expression
lifespan increased 30% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: foxo over-expression
lifespan increased 17% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Fwd over-expression
lifespan increased 8% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Gclc over-expression
lifespan increased 50% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Gclm over-expression
lifespan increased 24% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: gig over-expression
lifespan increased 12% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: GLaz over-expression
lifespan increased 29% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: GLaz over-expression
lifespan increased 45% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: GSR over-expression
lifespan increased 300% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Hsp26 over-expression
lifespan increased 30% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Hsp27 over-expression
lifespan increased 30% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: hsp68 over-expression
lifespan increased 20% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: hsp70 over-expression
lifespan increased (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: MSRA over-expression
lifespan increased 70% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: NF1 over-expression
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: NF1 over-expression
lifespan increased 68% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Pcmt over-expression
lifespan increased 35.5% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Pcmt over-expression
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Pka-C1 over-expression
lifespan increased 30% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: POSH over-expression
lifespan increased 14% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Rdh over-expression
lifespan increased 7% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Sod1 over-expression
lifespan increased 33% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Sod2 RNAi knockdown
lifespan increased 81% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: sug over-expression
lifespan increased 7% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: TrxT over-expression
lifespan increased 15% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Tsc1 over-expression
lifespan increased 14% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: UCP2 over-expression
lifespan increased 20% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: VhaSFD over-expression
lifespan increased 7.5% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: NIP RNAi knockdown
median lifespan decreased -75% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: NIP RNAi knockdown
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Lifespan Observation Drosophila melanogaster female
  • Environment Intervention: Stachys lavandulifolia extract
mean lifespan increased 35.62% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Environment Intervention: Stachys lavandulifolia extract
mean lifespan increased 55.74% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan decreased -7.89% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) male
  • Gene Intervention: Bmcp loss of function
mean lifespan decreased -21.57% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 37.4% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) male
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 26.32% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO)
  • Gene Intervention: Bmcp loss of function
mean lifespan decreased -8.85% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) male
  • Gene Intervention: Bmcp loss of function
mean lifespan decreased -17.52% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 3.24% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO)
  • Gene Intervention: Bmcp loss of function
lifespan increased 0.95%
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 17.4% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) male
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 4.56% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 0.7%
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Lifespan Observation Drosophila melanogaster (UCP5KO) male
  • Gene Intervention: Bmcp loss of function
mean lifespan decreased -3.47%
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: car loss of function
max lifespan increased 30% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: cat over-expression
  • Gene Intervention: sod1 over-expression
lifespan increased 33% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: cct1 over-expression
lifespan increased 7% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: Cdk5 loss of function
mean lifespan decreased -36.36% (significant)
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Lifespan Observation Drosophila melanogaster male
  • Gene Intervention: CG7207 loss of function
mean lifespan decreased -75% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Gene Intervention: CG7207 loss of function
mean lifespan decreased -71.43% (significant)
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Lifespan Observation Drosophila melanogaster (w1118)
  • Compound Intervention: phenylbutyrate (10 mM)
median lifespan increased 27.27% (significant)
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Lifespan Observation Drosophila melanogaster (DJ-1βA286)
  • Gene Intervention: dj-1beta loss of function
mean lifespan decreased -24% (significant)
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Lifespan Observation Drosophila melanogaster
  • Gene Intervention: DLP loss of function
mean lifespan increased 20% (significant)
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Lifespan Observation Drosophila melanogaster male
  • Gene Intervention: SOD1 (human SOD1 driven by D42-GAL4) over-expression
mean lifespan increased 16.09% (significant)
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Lifespan Observation Drosophila melanogaster male
  • Gene Intervention: SOD1 (x39) loss of function
mean lifespan decreased -96.17% (significant)
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Lifespan Observation Drosophila melanogaster male
  • Gene Intervention: SOD1 (human SOD1 driven by D42-GAL4) over-expression
  • Gene Intervention: SOD1 (x39) loss of function
mean lifespan decreased -67.43% (significant)
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Lifespan Observation Drosophila melanogaster male
  • Gene Intervention: SOD1 (human SOD1 driven by D42-GAL4) over-expression
  • Gene Intervention: SOD1 (x39) loss of function
mean lifespan decreased -27.2% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSODX1) over-expression
mean lifespan increased 34.51% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD2C) over-expression
mean lifespan increased 25.43% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD2C) over-expression
mean lifespan increased 32.51% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD3A) over-expression
mean lifespan increased 27.27% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD3A) over-expression
mean lifespan increased 11.93% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD2A) over-expression
mean lifespan increased 9.78% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD2A) over-expression
mean lifespan increased 12.75% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD3C) over-expression
mean lifespan increased 11.86% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD3C) over-expression
mean lifespan increased 3%
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD2E) over-expression
mean lifespan decreased -2.14%
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSOD2E) over-expression
mean lifespan increased 5.06%
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: CAT (CAT2A2) over-expression
mean lifespan decreased -6.86% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: CAT (CAT2A2) over-expression
mean lifespan decreased -8.2% (significant)
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Lifespan Observation Drosophila melanogaster (FLP3) male
  • Gene Intervention: SOD2 (mSODX1) over-expression
  • Gene Intervention: CAT (CAT2A2) over-expression
mean lifespan increased 7.43% (significant)
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