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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: petite
mean lifespan increased 31.88% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9)
  • Gene Intervention: RTG2 deletion / null
  • Environment Intervention: petite
lifespan decreased -6.84%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
median lifespan increased 63.64% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
  • Environment Intervention: dietary restriction
median lifespan increased 109.09% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SOD1 over-expression
  • Gene Intervention: CTT1 over-expression
lifespan decreased -2%
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Lifespan Observation Saccharomyces cerevisiae (YPK9)
  • Gene Intervention: CIT2 over-expression
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: CIT2 deletion / null
mean lifespan decreased -1.1%
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Lifespan Observation Saccharomyces cerevisiae (YPK9)
  • Gene Intervention: CIT2 _ over-expression
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Lifespan Observation Saccharomyces cerevisiae (YPK9)
  • Gene Intervention: CIT2 _ deletion / null
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -37.97% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -33.16% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
mean lifespan increased 37.97% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Compound Intervention: antimycin a (2 micrograms per milliliter)
mean lifespan decreased -3.77%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: COX4 deletion / null
mean lifespan increased 20% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RAS2 deletion / null
mean lifespan decreased -28.51% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RAS2 deletion / null
  • Environment Intervention: petite
mean lifespan decreased -28.51% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: petite
mean lifespan increased 31.14% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
median lifespan increased 81.82% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
median lifespan increased 53.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG2 deletion / null
  • Environment Intervention: dietary restriction
median lifespan increased 66.67% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG2 deletion / null
median lifespan decreased -26.67% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: LAG1 deletion / null
  • Gene Intervention: LAG1 (pLAG416[pLAG1::LAG1]) normal
mean lifespan decreased -9.81%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: LAG1 deletion / null
  • Gene Intervention: LAG1Hs (pMZ207[pLAG1::LAG1Hs]) normal
mean lifespan decreased -23.36% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 73.95% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
mean lifespan increased 103.36% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 97.48% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 139.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 142.86% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
  • Environment Intervention: dietary restriction
mean lifespan increased 157.98% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RPD3 deletion / null
  • Environment Intervention: dietary restriction
  • Environment Intervention: dietary restriction
mean lifespan increased 78.99% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 59.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HDA1 deletion / null
mean lifespan decreased -7.52%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HDA1 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 106.77% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 83.46% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HDA1 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 106.77% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
  • Environment Intervention: dietary restriction
mean lifespan increased 98.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HDA1 deletion / null
  • Environment Intervention: dietary restriction
  • Environment Intervention: dietary restriction
mean lifespan increased 102.26% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 32% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -46.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan decreased -27.2% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 102.29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -37.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan decreased -16.03% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: temperature
mean lifespan increased 34.09% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: PHB1 deletion / null
mean lifespan decreased -3.54%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: PHB2 deletion / null
mean lifespan decreased -3.54%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: PHB1 deletion / null
  • Gene Intervention: PHB2 deletion / null
mean lifespan decreased -4.55%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: rho0 deletion / null
mean lifespan increased 31.14% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: rho0 deletion / null
  • Gene Intervention: PHB1 deletion / null
mean lifespan decreased -31.74% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: rho0 deletion / null
  • Gene Intervention: PHB2 deletion / null
mean lifespan decreased -31.14% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: rho0 deletion / null
  • Gene Intervention: PHB1 deletion / null
  • Gene Intervention: PHB2 deletion / null
mean lifespan decreased -58.08% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RAS2 deletion / null
mean lifespan decreased -20.75% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RAS2 deletion / null
  • Gene Intervention: PHB1 deletion / null
mean lifespan decreased -30.66% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: rho0 deletion / null
mean lifespan decreased -18.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: LAC1 deletion / null
mean lifespan increased 8.19%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: rho0 deletion / null
mean lifespan increased 20.69% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: rho0 deletion / null
  • Gene Intervention: GCN5 deletion / null
mean lifespan decreased -38.42% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: GCN5 deletion / null
mean lifespan decreased -20.59% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 64.29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: dietary restriction
mean lifespan increased 114.29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HAP4 deletion / null
mean lifespan decreased -7.14%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HAP4 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 14.29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: HAP4 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 42.86% (significant)
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