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Showing results 1 - 45 of 45:
Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 34.68% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 )
  • Gene Intervention: SIR3 deletion / null
lifespan decreased -15.89% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR4 deletion / null
lifespan decreased -12.15% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: HML deletion / null
lifespan decreased -50% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 (R345A) loss of function
  • Gene Intervention: HML deletion / null
mean lifespan decreased (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -44.86% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 25.22% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Compound Intervention: resveratrol (100 micromolar)
mean lifespan increased 5.5%
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Environment Intervention: dietary restriction
lifespan decreased -34.15% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Environment Intervention: dietary restriction
lifespan decreased -23.17% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Environment Intervention: dietary restriction
lifespan decreased -8.13% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: HST4 deletion / null
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -52.17% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR4 deletion / null
mean lifespan decreased -12.15% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR4 deletion / null
  • Gene Intervention: HML deletion / null
mean lifespan increased 3.7%
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR4 deletion / null
mean lifespan decreased -15.74% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR3 deletion / null
mean lifespan decreased -25.12% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR3 deletion / null
  • Gene Intervention: HML deletion / null
mean lifespan increased 4.93%
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: HML deletion / null
mean lifespan decreased -44.39% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -44.86% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR3 deletion / null
mean lifespan decreased -25.49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR4 deletion / null
mean lifespan decreased -24.51% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: MATalpha over-expression
mean lifespan decreased -25.49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: HDF1 deletion / null
mean lifespan decreased -18.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: HDF2 deletion / null
mean lifespan decreased -32.55% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: DNL4 deletion / null
mean lifespan decreased -1.27%
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Environment Intervention: diploidization
mean lifespan decreased -15.35% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Environment Intervention: Mating type conversion
mean lifespan increased 2.93%
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Environment Intervention: ERC release
mean lifespan decreased -23.3% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR4 deletion / null
mean lifespan decreased -23.3% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR4 deletion / null
  • Environment Intervention: ERC release
mean lifespan decreased -26.14% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 30.43% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: HML deletion / null
mean lifespan decreased -37.2% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: HML deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 5.8%
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 25.22% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -52.17% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 over-expression
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -7.39%
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 over-expression
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 32.43% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 30.63% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Environment Intervention: Dietary restriction
median lifespan increased 400% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) matalpha
  • Environment Intervention: pH 6 buffering
median lifespan increased 450% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Environment Intervention: Dietary restriction
median lifespan increased 140% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Environment Intervention: Dietary restriction
median lifespan increased 140% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 140% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 140% (significant)
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