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Showing results 1 - 100 of 456:
Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -47% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: sgs1 deletion / null
mean lifespan decreased -60% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: rad52 deletion / null
mean lifespan decreased -62% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: rad52 deletion / null
mean lifespan decreased -62% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hpr1 deletion / null
mean lifespan decreased -62% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: phb1 deletion / null
mean lifespan decreased -47% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: phb2 deletion / null
mean lifespan decreased -45% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: mpt5 deletion / null
mean lifespan decreased -36% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: sod1 deletion / null
mean lifespan decreased -89% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: srs2 deletion / null
mean lifespan decreased -42% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: ras2 deletion / null
mean lifespan decreased -30% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: sin3 deletion / null
mean lifespan decreased -29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: cyt1 deletion / null
mean lifespan decreased -36% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hst3 deletion / null
mean lifespan decreased -32% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: pde2 deletion / null
mean lifespan decreased -29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: soh1 deletion / null
mean lifespan decreased -23% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: snf4 deletion / null
mean lifespan decreased -19% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: rtg2 deletion / null
mean lifespan decreased -23% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hst1 deletion / null
mean lifespan decreased -12% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: slt2 deletion / null
mean lifespan decreased -12% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hsc82 deletion / null
mean lifespan decreased -17% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: cdc73 deletion / null
mean lifespan decreased -14%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hog1 deletion / null
mean lifespan decreased -12%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: rtg3 deletion / null
mean lifespan decreased -7%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hst4 deletion / null
mean lifespan decreased -7%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: rad16 deletion / null
mean lifespan decreased -8%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: rpd3 deletion / null
mean lifespan decreased -5%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: sir3 deletion / null
mean lifespan decreased -9%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: sir4 deletion / null
mean lifespan decreased -7%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hst2 deletion / null
mean lifespan decreased -5%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: cpr7 deletion / null
mean lifespan decreased -4%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: rho0 deletion / null
mean lifespan decreased -1%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: ssd1 deletion / null
mean lifespan decreased -3%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hsp104 deletion / null
mean lifespan increased 7%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: zds1 deletion / null
mean lifespan increased 6%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: lag1 deletion / null
mean lifespan increased 7%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: sip2 deletion / null
mean lifespan increased 6.34%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: lag2 deletion / null
mean lifespan increased 10%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: pnc1 deletion / null
mean lifespan increased 5%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: uth1 deletion / null
mean lifespan increased 7%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: sod2 deletion / null
mean lifespan increased 10%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: ras1 deletion / null
mean lifespan increased 9%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: cpr7 deletion / null
mean lifespan increased 16%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: scp1 deletion / null
mean lifespan increased 13% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: zds2 deletion / null
mean lifespan increased 13% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: gpr1 deletion / null
mean lifespan increased 28% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: fob1 sir2 deletion / null
mean lifespan increased 14% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 31% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 24% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: sch9 deletion / null
mean lifespan increased 38% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hxk2 deletion / null
mean lifespan increased 34% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 41.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 30.71% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPR1 deletion / null
mean lifespan increased 28.46% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: HXK2 deletion / null
mean lifespan increased 37.45% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: HXK2 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 80.9% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 48.24% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: HXK2 deletion / null
mean lifespan increased 43.92% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 59.49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 36.86% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPA2 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 113.73% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -47.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: HXK2 deletion / null
mean lifespan decreased -53.56% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: GPA2 deletion / null
mean lifespan decreased -56.18% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 4.84%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: HXK2 deletion / null
mean lifespan increased 70.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 92.45% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan increased 32.66% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 14.11% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 21.37% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 29.44% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan increased 69.35% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan increased 64.52% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 32.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 over-expression
  • Environment Intervention: Dietary restriction
mean lifespan increased 62.07% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 21.84% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 130% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 80% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: pex5 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan decreased -70% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: pex5 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan decreased -50% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: pex5 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan decreased -20% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: pex5 deletion / null
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: lithocholic acid (50 micromolar)
mean lifespan increased 83.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: resveratrol (10 micromolar)
mean lifespan decreased -6.12%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: resveratrol (100 micromolar)
mean lifespan increased 6.53%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: resveratrol (10 micromolar)
mean lifespan decreased -3.29%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: BRE5 deletion / null
mean lifespan increased 29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 21% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 42% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: IDH2 deletion / null
mean lifespan increased 31% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: REI1 deletion / null
mean lifespan increased 38% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: REI1 deletion / null
mean lifespan increased 52% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: ROM2 deletion / null
mean lifespan increased 49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) mata
  • Gene Intervention: ROM2 deletion / null
mean lifespan increased 16% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: RPL31A deletion / null
mean lifespan increased 35% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: RPL6B deletion / null
mean lifespan increased 23% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: RPL6B deletion / null
mean lifespan increased 23% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 23% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 21% (significant)
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