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Showing results 1 - 100 of 507:
Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: PDE2 deletion / null
mean lifespan decreased -25.69% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: QPT1 deletion / null
mean lifespan increased 10.24%
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD1 deletion / null
mean lifespan decreased -5%
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD26 deletion / null
mean lifespan decreased -4.09%
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD51 deletion / null
lifespan decreased -43.48% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD52 deletion / null
mean lifespan decreased -69.79% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD7 deletion / null
mean lifespan increased 0.45%
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Lifespan Observation Saccharomyces cerevisiae (YSK663) matalpha
  • Gene Intervention: RPD3 deletion / null
median lifespan increased 40.91% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: STE12 deletion / null
mean lifespan increased 5.77%
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: STE4 deletion / null
mean lifespan increased 1.92%
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: SIR4 deletion / null
median lifespan decreased -10.53% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: SIR4 (sir4-42) non-null semi-dominant
median lifespan increased 47.37% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -47% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: sip2 deletion / null
mean lifespan increased 6.34%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 41.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 30.71% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPR1 deletion / null
mean lifespan increased 28.46% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: HXK2 deletion / null
mean lifespan increased 37.45% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: HXK2 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 80.9% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 48.24% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: HXK2 deletion / null
mean lifespan increased 43.92% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 59.49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 36.86% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPA2 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 113.73% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -47.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: HXK2 deletion / null
mean lifespan decreased -53.56% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: GPA2 deletion / null
mean lifespan decreased -56.18% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 4.84%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: HXK2 deletion / null
mean lifespan increased 70.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 92.45% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan increased 32.66% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 14.11% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 21.37% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 29.44% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan increased 69.35% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan increased 64.52% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AT) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 3.94% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AT) matalpha
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 2.84%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 32.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 over-expression
  • Environment Intervention: Dietary restriction
mean lifespan increased 62.07% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 21.84% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 130% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 80% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: pex5 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan decreased -70% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: pex5 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan decreased -50% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: pex5 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan decreased -20% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: pex5 deletion / null
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: lithocholic acid (50 micromolar)
mean lifespan increased 83.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AT) matalpha
  • Gene Intervention: SIR2 over-expression
mean lifespan decreased -2.58%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: resveratrol (10 micromolar)
mean lifespan decreased -6.12%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: resveratrol (100 micromolar)
mean lifespan increased 6.53%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: resveratrol (10 micromolar)
mean lifespan decreased -3.29%
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Lifespan Observation Saccharomyces cerevisiae (PSY316AR) matalpha
  • Compound Intervention: resveratrol (100 micromolar)
mean lifespan decreased -5.63%
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Lifespan Observation Saccharomyces cerevisiae (PSY316AR) matalpha
  • Compound Intervention: resveratrol (10 micromolar)
mean lifespan increased 12.21%
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Lifespan Observation Saccharomyces cerevisiae (PSY316AT) matalpha
  • Compound Intervention: resveratrol (100 micromolar)
mean lifespan increased 5.58%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: BRE5 deletion / null
mean lifespan increased 29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 21% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 42% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: IDH2 deletion / null
mean lifespan increased 31% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: REI1 deletion / null
mean lifespan increased 38% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: REI1 deletion / null
mean lifespan increased 52% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: ROM2 deletion / null
mean lifespan increased 49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: RPL31A deletion / null
mean lifespan increased 35% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: RPL6B deletion / null
mean lifespan increased 23% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: RPL6B deletion / null
mean lifespan increased 23% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 23% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 21% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: URE2 deletion / null
mean lifespan increased 15% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: YBR238C deletion / null
mean lifespan increased 25% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: YBR238C deletion / null
mean lifespan increased 21% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: YBR255W deletion / null
mean lifespan increased 34% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: YBR255W deletion / null
mean lifespan increased 19% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: YBR266C deletion / null
mean lifespan increased 37% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: YOR135W deletion / null
mean lifespan increased 22% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 21.28% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: TOR1 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 20.43% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: dietary restriction
mean lifespan increased 20.85% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: dietary restriction
mean lifespan increased 12.79% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: SCH9 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 15.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: SCH9 deletion / null
mean lifespan increased 41.86% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 22.31% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: TOR1 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 66.53% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 22.31% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: SCH9 deletion / null
  • Environment Intervention: dietary restriction
mean lifespan increased 116.18% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: SIR2 deletion / null
mean lifespan increased 2.45%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 33.47% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: SCH9 deletion / null
mean lifespan increased 49.39% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 19.25% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: methionine sulfoximine (1 millimolar)
mean lifespan increased 22.92% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: methionine sulfoximine (100 micromolar)
mean lifespan increased 19.37% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: methionine sulfoximine (2.5 mM)
mean lifespan increased 6.72%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: methionine sulfoximine (10 mM)
mean lifespan decreased -56.92% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: methionine sulfoximine (50 micromolar)
mean lifespan increased 12.65%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: rho0
mean lifespan increased 3.85%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: rho0
  • Environment Intervention: dietary restriction
mean lifespan increased 29.49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: dietary restriction
mean lifespan increased 29.49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AUT) matalpha
  • Environment Intervention: rho0
mean lifespan decreased -42.79% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AUT) matalpha
  • Environment Intervention: rho0
  • Environment Intervention: dietary restriction
mean lifespan increased 22.07% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AUT) matalpha
  • Environment Intervention: dietary restriction
mean lifespan increased 42.79% (significant)
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