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Showing results 1 - 100 of 386:
Lifespan Observation Saccharomyces cerevisiae (W303-1A) mata
  • Gene Intervention: ADA1 deletion / null
mean lifespan decreased -86.53% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: petite
mean lifespan increased 31.88% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SP1) mata
  • Gene Intervention: RAS1 deletion / null
mean lifespan increased 23.26% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SP1) mata
  • Gene Intervention: RAS1 over-expression
mean lifespan decreased -1.11%
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Lifespan Observation Saccharomyces cerevisiae (SP1) mata
  • Gene Intervention: RAS2 over-expression
lifespan increased 42.94% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303-1A) mata
  • Gene Intervention: RIF1 deletion / null
median lifespan decreased -29.26% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
median lifespan increased 63.64% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
  • Environment Intervention: dietary restriction
median lifespan increased 109.09% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W3031-A) mata
  • Gene Intervention: SGS1 deletion / null
mean lifespan decreased -61.22% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YB332) mata
  • Gene Intervention: NMT1 (451D) loss of function
mean lifespan decreased -47.27% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YB332) mata
  • Gene Intervention: SIP1 deletion / null
mean lifespan decreased -18% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YB332) mata
  • Gene Intervention: SIP2 deletion / null
mean lifespan decreased -51.61% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 34.68% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR4 deletion / null
lifespan decreased -12.15% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: SOD1 over-expression
  • Gene Intervention: CTT1 over-expression
lifespan decreased -2%
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: CIT2 deletion / null
mean lifespan decreased -1.1%
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: HML deletion / null
lifespan decreased -50% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Gene Intervention: SIR2 (R345A) loss of function
  • Gene Intervention: HML deletion / null
mean lifespan decreased (significant)
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Lifespan Observation Saccharomyces cerevisiae (SP1) mata
  • Gene Intervention: RAS2 deletion / null
lifespan decreased -22.9% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -44.86% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 25.22% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303-1A) mata
  • Gene Intervention: TLC1 (ADH-tTLC1) over-expression
mean lifespan decreased -20.08% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Compound Intervention: rapamycin (0.55 nM)
median lifespan increased 20% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Compound Intervention: caffeine (0.4 mM)
median lifespan increased 20% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Compound Intervention: resveratrol (100 micromolar)
mean lifespan increased 5.5%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: BRE5 deletion / null
mean lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: IDH2 deletion / null
mean lifespan increased 18% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: REI1 deletion / null
mean lifespan increased 47% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) mata
  • Gene Intervention: ROM2 deletion / null
mean lifespan increased 16% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL31A deletion / null
mean lifespan increased 59% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL6B deletion / null
mean lifespan increased 33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 22% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: URE2 deletion / null
mean lifespan increased 21% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: YBR238C deletion / null
mean lifespan increased 34% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: YBR255W deletion / null
mean lifespan increased 25% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: YBR266C deletion / null
mean lifespan increased 47% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: YOR135W deletion / null
mean lifespan increased 18% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 25.3% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL31A deletion / null
mean lifespan increased 59.29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL6B deletion / null
mean lifespan increased 32.41% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Environment Intervention: dietary restriction
lifespan decreased -34.15% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Environment Intervention: dietary restriction
lifespan decreased -23.17% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Environment Intervention: dietary restriction
lifespan decreased -8.13% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: HST4 deletion / null
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: YPT6 deletion / null
mean lifespan increased 10.7% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: YGR130C deletion / null
mean lifespan increased 19.2% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: TIS11 deletion / null
mean lifespan increased 25.7% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: SIS2 deletion / null
mean lifespan increased 27.7% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: SAM1 deletion / null
mean lifespan increased 12.9% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: PMR1 deletion / null
mean lifespan increased 14.7% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: PKH2 deletion / null
mean lifespan increased 14.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: INP51 deletion / null
mean lifespan increased 10.6% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: IDH1 deletion / null
mean lifespan increased 9% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: HSE1 deletion / null
mean lifespan increased 13.7% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: DBP3 deletion / null
mean lifespan increased 21.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: ALG12 deletion / null
mean lifespan increased 23.8% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: ADH1 deletion / null
mean lifespan increased 14.9% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: TOR1 deletion / null
mean lifespan increased 21.6% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: TIF4631 deletion / null
mean lifespan increased 22.8% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: TIF2 deletion / null
mean lifespan increased 14.9% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: TIF1 deletion / null
mean lifespan increased 14.6% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: SPT4 deletion / null
mean lifespan increased 38.7% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL9A deletion / null
mean lifespan increased 19.7% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL6B deletion / null
mean lifespan increased 32.7% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL19A deletion / null
mean lifespan increased 48.2% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: INP53 deletion / null
mean lifespan increased 10.2% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: IDH2 deletion / null
mean lifespan increased 16.9% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: AFG3 deletion / null
mean lifespan increased 21.4% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 deletion / null
mean lifespan decreased -52.17% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL22A deletion / null
mean lifespan increased 90.93% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL20B deletion / null
mean lifespan increased 80.99% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL21B deletion / null
mean lifespan increased 80.35% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL13A deletion / null
mean lifespan increased 60.91% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL31A deletion / null
mean lifespan increased 59.41% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL34B deletion / null
mean lifespan increased 58.1% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPS12 deletion / null
mean lifespan increased 52.94% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL19A deletion / null
mean lifespan increased 48.16% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL39 deletion / null
mean lifespan increased 46.69% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPP2B deletion / null
mean lifespan increased 44.92% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL23A deletion / null
mean lifespan increased 40.54% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL29 deletion / null
mean lifespan increased 35.47% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL43B deletion / null
mean lifespan increased 32.88% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL6B deletion / null
mean lifespan increased 32.67% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL9B deletion / null
mean lifespan increased 31.76% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPS11A deletion / null
mean lifespan increased 26.12% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL37B deletion / null
mean lifespan increased 18.14%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL7A deletion / null
mean lifespan increased 17.37% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL9A deletion / null
mean lifespan increased 15.37%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL17B deletion / null
mean lifespan increased 11.06%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL34A deletion / null
mean lifespan increased 10.35%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPS17A deletion / null
mean lifespan increased 10.12%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL23B deletion / null
mean lifespan increased 10.12%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPP2A deletion / null
mean lifespan increased 8.28%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL12A deletion / null
mean lifespan increased 7.39%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL8B deletion / null
mean lifespan increased 4.87%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPS21A deletion / null
mean lifespan increased 3.82%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPS1A deletion / null
mean lifespan increased 2.77%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL20A deletion / null
mean lifespan increased 1.65%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL1B deletion / null
mean lifespan increased 1.17%
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: RPL12B deletion / null
mean lifespan decreased -0.42%
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