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Showing results 1 - 100 of 611:
Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Environment Intervention: petite
mean lifespan increased 31.88% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: QPT1 deletion / null
mean lifespan increased 10.24%
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Lifespan Observation Saccharomyces cerevisiae (PSY316) matalpha
  • Gene Intervention: RAD7 deletion / null
mean lifespan increased 0.45%
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Lifespan Observation Saccharomyces cerevisiae (DBY747)
  • Gene Intervention: RAD9 deletion / null
mean lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SP1) mata
  • Gene Intervention: RAS1 deletion / null
mean lifespan increased 23.26% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SP1) mata
  • Gene Intervention: RAS2 over-expression
lifespan increased 42.94% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YSK663) matalpha
  • Gene Intervention: RPD3 deletion / null
median lifespan increased 40.91% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
median lifespan increased 63.64% (significant)
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Lifespan Observation Saccharomyces cerevisiae (YPK9) mata
  • Gene Intervention: RTG3 deletion / null
  • Environment Intervention: dietary restriction
median lifespan increased 109.09% (significant)
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Lifespan Observation Saccharomyces cerevisiae (DBY746)
  • Gene Intervention: SCH9 (mTn) non-null recessive
mean lifespan increased 33.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 34.68% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: STE12 deletion / null
mean lifespan increased 5.77%
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: STE4 deletion / null
mean lifespan increased 1.92%
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Lifespan Observation Saccharomyces cerevisiae (PSY316)
  • Gene Intervention: CDC25 non-null recessive
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (W3031-A)
  • Gene Intervention: CDC6 non-null recessive
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303)
  • Gene Intervention: ZDS1 deletion / null
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316)
  • Gene Intervention: HAP4 over-expression
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (DBY746)
  • Gene Intervention: CYR1 (mTn) non-null recessive
lifespan increased 90% (significant)
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Lifespan Observation Saccharomyces cerevisiae (EG103)
  • Gene Intervention: SOD2 over-expression
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (EG103)
  • Gene Intervention: SOD1 over-expression
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (DBY746)
  • Gene Intervention: CTT1 over-expression
  • Gene Intervention: sod1 over-expression
lifespan increased 10% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BKY1-14c) matalpha
  • Gene Intervention: SIR4 (sir4-42) non-null semi-dominant
median lifespan increased 47.37% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: AGP1 deletion / null
lifespan increased 33% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: HAP4 over-expression
lifespan increased 40% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: HST2 over-expression
lifespan increased 14% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: LAG2 over-expression
lifespan increased 36% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: MPT5 over-expression
lifespan increased 25% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: NDE1 over-expression
lifespan increased 22.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: NDE1 over-expression
lifespan increased 22.5% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: NPT1 over-expression
lifespan increased 60% (significant)
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Lifespan Observation Saccharomyces cerevisiae (SP1)
  • Gene Intervention: RAS2 over-expression
lifespan increased 43% (significant)
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Lifespan Observation Saccharomyces cerevisiae (W303AR5 ) mata
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 25.22% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: SNF1 over-expression
lifespan increased 26% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: Sod1 over-expression
lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: Sod2 over-expression
lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: SSD1 over-expression
lifespan increased 50% (significant)
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Lifespan Observation Saccharomyces cerevisiae
  • Gene Intervention: Ump1 over-expression
lifespan increased (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hsp104 deletion / null
mean lifespan increased 7%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: zds1 deletion / null
mean lifespan increased 6%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: lag1 deletion / null
mean lifespan increased 7%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: sip2 deletion / null
mean lifespan increased 6.34%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: lag2 deletion / null
mean lifespan increased 10%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: pnc1 deletion / null
mean lifespan increased 5%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: uth1 deletion / null
mean lifespan increased 7%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: sod2 deletion / null
mean lifespan increased 10%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: ras1 deletion / null
mean lifespan increased 9%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: cpr7 deletion / null
mean lifespan increased 16%
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: scp1 deletion / null
mean lifespan increased 13% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: zds2 deletion / null
mean lifespan increased 13% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: gpr1 deletion / null
mean lifespan increased 28% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: fob1 sir2 deletion / null
mean lifespan increased 14% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 31% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 24% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: sch9 deletion / null
mean lifespan increased 38% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742)
  • Gene Intervention: hxk2 deletion / null
mean lifespan increased 34% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 41.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 30.71% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPR1 deletion / null
mean lifespan increased 28.46% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: HXK2 deletion / null
mean lifespan increased 37.45% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: HXK2 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 80.9% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 48.24% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: HXK2 deletion / null
mean lifespan increased 43.92% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 59.49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 36.86% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: GPA2 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 113.73% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 4.84%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: HXK2 deletion / null
mean lifespan increased 70.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Gene Intervention: GPA2 deletion / null
mean lifespan increased 92.45% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Compound Intervention: rapamycin (0.55 nM)
median lifespan increased 20% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Compound Intervention: caffeine (0.4 mM)
median lifespan increased 20% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan increased 32.66% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 14.11% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 21.37% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 29.44% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan increased 69.35% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 deletion / null
  • Gene Intervention: FOB1 deletion / null
  • Environment Intervention: Dietary restriction
mean lifespan increased 64.52% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AT) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 3.94% (significant)
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Lifespan Observation Saccharomyces cerevisiae (PSY316AT) matalpha
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 2.84%
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 over-expression
mean lifespan increased 32.57% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Gene Intervention: SIR2 over-expression
  • Environment Intervention: Dietary restriction
mean lifespan increased 62.07% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 21.84% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 130% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Environment Intervention: Dietary restriction
mean lifespan increased 80% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: lithocholic acid (50 micromolar)
mean lifespan increased 83.33% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Compound Intervention: resveratrol (100 micromolar)
mean lifespan increased 6.53%
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Lifespan Observation Saccharomyces cerevisiae (W303AR5) mata
  • Compound Intervention: resveratrol (100 micromolar)
mean lifespan increased 5.5%
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Lifespan Observation Saccharomyces cerevisiae (PSY316AR) matalpha
  • Compound Intervention: resveratrol (10 micromolar)
mean lifespan increased 12.21%
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Lifespan Observation Saccharomyces cerevisiae (PSY316AT) matalpha
  • Compound Intervention: resveratrol (100 micromolar)
mean lifespan increased 5.58%
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: BRE5 deletion / null
mean lifespan increased 29% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: BRE5 deletion / null
mean lifespan increased 30% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 21% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: FOB1 deletion / null
mean lifespan increased 42% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: IDH2 deletion / null
mean lifespan increased 31% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: IDH2 deletion / null
mean lifespan increased 18% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: REI1 deletion / null
mean lifespan increased 38% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: REI1 deletion / null
mean lifespan increased 52% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4741) mata
  • Gene Intervention: REI1 deletion / null
mean lifespan increased 47% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) matalpha
  • Gene Intervention: ROM2 deletion / null
mean lifespan increased 49% (significant)
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Lifespan Observation Saccharomyces cerevisiae (BY4742 ) mata
  • Gene Intervention: ROM2 deletion / null
mean lifespan increased 16% (significant)
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