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Showing results 1 - 100 of 115:
Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: NIP RNAi knockdown
median lifespan decreased -75% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: NIP RNAi knockdown
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Lifespan Observation Drosophila melanogaster female
  • Environment Intervention: Stachys lavandulifolia extract
mean lifespan increased 35.62% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Environment Intervention: Stachys lavandulifolia extract
mean lifespan increased 55.74% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan decreased -7.89% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 37.4% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 3.24% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 17.4% (significant)
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Lifespan Observation Drosophila melanogaster (UCP5KO) female
  • Gene Intervention: Bmcp loss of function
mean lifespan increased 0.7%
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Lifespan Observation Drosophila melanogaster female
  • Gene Intervention: CG7207 loss of function
mean lifespan decreased -71.43% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Compound Intervention: phenylbutyrate (10 mM)
median lifespan increased 18.18% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Compound Intervention: phenylbutyrate (10 mM)
mean lifespan increased 50% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Compound Intervention: spermidine (0.01 mM)
median lifespan increased 25% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Compound Intervention: spermidine (0.1 mM)
median lifespan increased 27.5% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Compound Intervention: spermidine (1 mM)
median lifespan increased 50% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: atg7 loss of function
  • Compound Intervention: spermidine (1 mM)
median lifespan decreased -12.5% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: atg7 loss of function
  • Compound Intervention: spermidine (0.1 mM)
median lifespan decreased -12.5% (significant)
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Lifespan Observation Drosophila melanogaster (w1118) female
  • Gene Intervention: atg7 loss of function
  • Compound Intervention: spermidine (0.01 mM)
median lifespan decreased -12.5% (significant)
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Lifespan Observation Drosophila melanogaster (Outbred population caught in early October 2006 in a vineyard ne) female
  • Environment Intervention: dietary restriction
median lifespan increased 24.24% (significant)
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Lifespan Observation Drosophila melanogaster (Outbred population caught in early October 2006 in a vineyard ne) female
  • Environment Intervention: dietary restriction
median lifespan increased 18.18% (significant)
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Lifespan Observation Drosophila melanogaster (Outbred population caught in early October 2006 in a vineyard ne) female
  • Environment Intervention: dietary restriction
median lifespan decreased -31.82% (significant)
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Lifespan Observation Drosophila melanogaster (W1118) female
  • Gene Intervention: Egm loss of function
median lifespan increased 19.5% (significant)
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Lifespan Observation Drosophila melanogaster (Dwarf) female
  • Gene Intervention: Inr loss of function
lifespan increased 85% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Gene Intervention: mnt deletion / null
mean lifespan decreased -32.26% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Gene Intervention: mnt deletion / null
mean lifespan decreased -16.13% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Gene Intervention: mys (xG) loss of function
mean lifespan increased 20.69% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Gene Intervention: mys (ts2) loss of function
mean lifespan increased 20% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Gene Intervention: p53 over-expression
lifespan increased 58% (significant)
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Lifespan Observation Drosophila melanogaster (K33) female
  • Gene Intervention: rut1 loss of function
median lifespan decreased -60% (significant)
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Lifespan Observation Drosophila melanogaster (K33) female
  • Gene Intervention: rut1 loss of function
max lifespan decreased -43.84% (significant)
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Lifespan Observation Drosophila melanogaster (K33) female
  • Gene Intervention: rut2080 loss of function
median lifespan decreased -56% (significant)
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Lifespan Observation Drosophila melanogaster (K33) female
  • Gene Intervention: rut2080 loss of function
max lifespan decreased -52.05% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 dominant negative
mean lifespan increased 10% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 dominant negative
mean lifespan increased 24.44% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 dominant negative
median lifespan increased 10.53% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 dominant negative
median lifespan increased 27.27% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 dominant negative
max lifespan increased 3.03% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 dominant negative
max lifespan increased 16.67% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
mean lifespan decreased (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
mean lifespan increased 5.88%
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
mean lifespan increased 11.36%
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
mean lifespan increased 10.2% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
mean lifespan decreased -7.84% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
median lifespan increased 1.59%
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
median lifespan increased 14.81%
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
median lifespan increased 4.35% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
median lifespan increased 15.38% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
median lifespan decreased -17.86% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
max lifespan increased 4.76%
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
max lifespan decreased -4.65%
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
max lifespan increased 5% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
max lifespan increased 2.5% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (259H) deletion / null
max lifespan decreased -7.32% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (159H) dominant negative
mean lifespan increased 17.24% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (159H) dominant negative
mean lifespan increased 13.89% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (159H) dominant negative
median lifespan increased 6.67% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (159H) dominant negative
median lifespan increased 23.53% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (159H) dominant negative
max lifespan increased 5.88% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (159H) dominant negative
max lifespan increased 21.43% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (R155H) dominant negative
mean lifespan increased 11.11% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (R155H) dominant negative
mean lifespan increased 21.43% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (R155H) dominant negative
median lifespan increased 17.65% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (R155H) dominant negative
median lifespan increased 23.81% (significant)
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (R155H) dominant negative
max lifespan decreased -3.33%
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Lifespan Observation Drosophila melanogaster (ELAV-GeneSwitch) female
  • Gene Intervention: Dmp53 (R155H) dominant negative
max lifespan increased 5.88% (significant)
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Lifespan Observation Drosophila melanogaster (S1-32) female
  • Gene Intervention: dFox21 over-expression
mean lifespan increased 26.32% (significant)
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Lifespan Observation Drosophila melanogaster (S1-32) female
  • Gene Intervention: dFox21 over-expression
median lifespan increased 38.89% (significant)
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Lifespan Observation Drosophila melanogaster (S1-32) female
  • Gene Intervention: dFox21 over-expression
max lifespan increased 15.63% (significant)
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Lifespan Observation Drosophila melanogaster (S1-32) female
  • Gene Intervention: Dmp53 (259H) dominant negative
  • Gene Intervention: dFox21 over-expression
mean lifespan increased 15.91% (significant)
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Lifespan Observation Drosophila melanogaster (S1-32) female
  • Gene Intervention: Dmp53 (259H) dominant negative
  • Gene Intervention: dFox21 over-expression
median lifespan increased 23.81% (significant)
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Lifespan Observation Drosophila melanogaster (S1-32) female
  • Gene Intervention: Dmp53 (259H) dominant negative
  • Gene Intervention: dFox21 over-expression
max lifespan increased 22.06% (significant)
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Lifespan Observation Drosophila melanogaster (w m4) female
  • Gene Intervention: Su(var)2-502/+ loss of function
max lifespan decreased -3.64% (significant)
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Lifespan Observation Drosophila melanogaster (w m4) female
  • Gene Intervention: Su(var)2-502/+ loss of function
median lifespan decreased -8.72% (significant)
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Lifespan Observation Drosophila melanogaster (w m4) female
  • Gene Intervention: Dp(2;2)P90/+ loss of function
median lifespan increased 6.05% (significant)
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Lifespan Observation Drosophila melanogaster (w m4) female
  • Gene Intervention: Dp(2;2)P90/+ loss of function
max lifespan decreased -4.18% (significant)
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Lifespan Observation Drosophila melanogaster (w m4) female
  • Gene Intervention: Su(var)2-1^01/+ loss of function
max lifespan increased 6.99% (significant)
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Lifespan Observation Drosophila melanogaster (w m4) female
  • Gene Intervention: Su(var)2-1^01/+ loss of function
median lifespan increased 2.78% (significant)
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Lifespan Observation Drosophila melanogaster (w m4) female
  • Gene Intervention: E2F^91/+ loss of function
median lifespan increased 2.54% (significant)
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Lifespan Observation Drosophila melanogaster (w m4) female
  • Gene Intervention: E2F^91/+ loss of function
max lifespan decreased -1.29% (significant)
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Lifespan Observation Drosophila melanogaster (Wild) female
  • Gene Intervention: chico loss of function
lifespan increased 36.16% (significant)
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Lifespan Observation Drosophila melanogaster (Wild) female
  • Gene Intervention: chico deletion / null
lifespan increased 57.56% (significant)
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
mean lifespan increased 7.14% (significant)
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
mean lifespan increased 10.39% (significant)
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
mean lifespan increased 9.33% (significant)
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
mean lifespan increased 9.33% (significant)
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
mean lifespan increased 14.29% (significant)
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
mean lifespan increased 17.14% (significant)
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
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Lifespan Observation Drosophila melanogaster (UGA UAS-HS) female
  • Gene Intervention: SOD over-expression
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Lifespan Observation Drosophila melanogaster (dFOXO21a/+) female
  • Gene Intervention: dFOXO deletion / null
  • Environment Intervention: Dietary restriction
median lifespan decreased -25% (significant)
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Lifespan Observation Drosophila melanogaster (dFOXO21a/+) female
  • Gene Intervention: dFOXO deletion / null
  • Environment Intervention: Dietary restriction
median lifespan increased 33.33% (significant)
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Lifespan Observation Drosophila melanogaster (dFOXO21a/+) female
  • Gene Intervention: dFOXO deletion / null
  • Environment Intervention: Dietary restriction
median lifespan decreased -47.3% (significant)
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Lifespan Observation Drosophila melanogaster (dFOXO21a/+) female
  • Gene Intervention: dFOXO deletion / null
  • Environment Intervention: Dietary restriction
median lifespan decreased -23.81% (significant)
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Lifespan Observation Drosophila melanogaster (dFOXO21a/+) female
  • Gene Intervention: dFOXO deletion / null
  • Environment Intervention: Dietary restriction
median lifespan decreased -37.84% (significant)
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Lifespan Observation Drosophila melanogaster (dFOXO21a/+) female
  • Gene Intervention: dFOXO deletion / null
  • Environment Intervention: Dietary restriction
median lifespan decreased -32.08% (significant)
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Lifespan Observation Drosophila melanogaster (dFOXO21a/+) female
  • Gene Intervention: dFOXO deletion / null
  • Environment Intervention: Dietary restriction
median lifespan decreased -50% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Gene Intervention: wdb over-expression
mean lifespan increased 13% (significant)
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Lifespan Observation Drosophila melanogaster female
  • Gene Intervention: lkb1 over-expression
mean lifespan increased 6.5% (significant)
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