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Showing results 1 - 100 of 2575:
Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: osm-5 (p802) unknown
mean lifespan increased 121.28% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: osm-6 (p811) unknown
mean lifespan increased 56.38% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: rad-8 non-null recessive
mean lifespan increased 33.33% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: sir-2.1 (geEx1) over-expression
mean lifespan increased 14.21% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: eat-1 (ad427) loss of function
mean lifespan increased 33.33% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: spe-10 (hc104) unknown
mean lifespan increased 26.16% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1370) unknown
mean lifespan increased 32.35% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (sa189) unknown
mean lifespan increased 133.33% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (sa193) unknown
mean lifespan increased 66.67% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: tax-2 (p671) unknown
mean lifespan increased 6.91%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: tax-4 (p678) unknown
mean lifespan increased 94.68% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: tkr-1 (Ex) over-expression
mean lifespan increased 91.02% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-1 unknown
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Lifespan Observation Caenorhabditis elegans (N2) male
  • Gene Intervention: unc-13 non-null recessive
median lifespan increased 76.78% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-15 unknown
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: unc-2 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-20 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-24 (e138) non-null recessive
mean lifespan increased 1.05%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-25 (e265) loss of function
mean lifespan increased 5.07%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-26 (e156) non-null recessive
mean lifespan increased 44.22% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-29 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-30 (e318) non-null recessive
mean lifespan decreased -21.76% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-32 (e189) unknown
median lifespan increased 4.12%
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Lifespan Observation Caenorhabditis elegans (N2) male
  • Gene Intervention: unc-32 (e189) unknown
median lifespan increased 58.29% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-4 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-46 (e177) non-null recessive
median lifespan decreased -0.46%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-47 (e367) non-null recessive
mean lifespan decreased -5.09%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-49 (e382) non-null recessive
lifespan increased 6.45%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-54 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-6 unknown
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: unc-7 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-78 unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-79 (e1068) non-null recessive
mean lifespan increased 11.06% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: unc-80 (qm2) non-null recessive
mean lifespan increased 6.53%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-11 (e1810) unknown
mean lifespan increased 45.21% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-13 (e1805) unknown
mean lifespan increased 32.98% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-2 (p801) unknown
mean lifespan increased 42.55% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: fer-15 (b26) non-null recessive
median lifespan decreased -11.76% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) female
  • Gene Intervention: fem-3 (e1996) unknown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: che-3 (e1124) unknown
mean lifespan increased 36.7% (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: nuo-2 RNAi knockdown
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: cco-1 RNAi knockdown
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: atp-3 RNAi knockdown
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: cyc-1 RNAi knockdown
lifespan increased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (mgDf50) loss of function
mean lifespan decreased -20.22% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-16 (mgDf50) loss of function
  • Gene Intervention: sir-2.1 (geIn3) over-expression
mean lifespan decreased -25.14% (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: hsf-1 RNAi knockdown
lifespan decreased (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: ced-3 non-null recessive
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-10 (e1387) unknown
mean lifespan increased 56.38% (significant)
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: scl-1 RNAi knockdown
lifespan decreased (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-19 (m86) unknown
mean lifespan increased 30.32% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-2 (e1370) unknown
mean lifespan increased 121.05% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: cul-1 RNAi knockdown
  • Gene Intervention: daf-2 (mu150) loss of function
mean lifespan increased 15.59% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: fbxa-121 RNAi knockdown
  • Gene Intervention: daf-2 (mu150) loss of function
mean lifespan decreased -31.75% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: frh-1 RNAi knockdown
mean lifespan increased 27.95% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-1 (pkIs503) over-expression
mean lifespan decreased -8.21% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-11 (pkIs539) over-expression
mean lifespan increased 20.57% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-15 (pkIs555) over-expression
mean lifespan decreased -17.16% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-2 (pkIs580) over-expression
mean lifespan increased 12.69% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-3 (pkIs508) over-expression
mean lifespan decreased -2.24%
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Lifespan Observation Caenorhabditis elegans (N2)
  • Gene Intervention: gpa-5 (pkIs379) over-expression
mean lifespan decreased -9.7% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-6 (pkIs519) over-expression
mean lifespan decreased -2.99%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-8 (pkIs527) over-expression
mean lifespan decreased -14.18% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: gpa-9 (pkIs531) over-expression
mean lifespan decreased -17.91% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: jnk-1 over-expression
mean lifespan increased 37.5% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: lin-23 RNAi knockdown
  • Gene Intervention: daf-2 (mu150) loss of function
lifespan decreased -29.37% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: sir-2.1 (geIn1) over-expression
lifespan increased 18.03% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: tkr-1 (Ex) over-expression
mean lifespan increased 65.23% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: Y38C1AA.3 over-expression
mean lifespan decreased -4.37%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: Y46G5A.6 RNAi knockdown
  • Gene Intervention: daf-2 loss of function
mean lifespan decreased -28.57% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: mpk-1 RNAi knockdown
mean lifespan decreased -16% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: mek-2 RNAi knockdown
mean lifespan decreased -10% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: lin-45 RNAi knockdown
mean lifespan decreased -9% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: mpk-1 RNAi knockdown
mean lifespan decreased -17% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: skn-1 RNAi knockdown
mean lifespan decreased -18% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: lip-1 RNAi knockdown
mean lifespan increased 8% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: daf-28 RNAi knockdown
mean lifespan increased 4% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: ins-39 RNAi knockdown
mean lifespan increased 8% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: lip-1 (zh15) loss of function
mean lifespan increased 24% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: lin-1 RNAi knockdown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: lin-31 RNAi knockdown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: rskn-1 RNAi knockdown
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: rskn-2 RNAi knockdown
mean lifespan increased 3%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: K08F8.1 RNAi knockdown
mean lifespan increased 1%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: mak-2 RNAi knockdown
mean lifespan increased 4%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: mnk-1 RNAi knockdown
mean lifespan increased 2%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Compound Intervention: U0126 (12.5 micromolar)
mean lifespan decreased -12% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok386) loss of function
mean lifespan increased 17.28% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok386) loss of function
mean lifespan increased 11.66% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok386) loss of function
mean lifespan increased 11.46% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok386) loss of function
mean lifespan increased 36.09% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok386) loss of function
mean lifespan increased 26.7% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok386) loss of function
mean lifespan increased 13.01% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok386) loss of function
mean lifespan increased 12.92% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok386) loss of function
mean lifespan increased 23.84% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok386) loss of function
mean lifespan increased 28.1% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (tm1862) loss of function
mean lifespan decreased -4.61%
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (tm1862) loss of function
mean lifespan decreased -12.8% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok701) loss of function
mean lifespan increased 20.9% (significant)
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Lifespan Observation Caenorhabditis elegans (N2) hermaphrodite
  • Gene Intervention: raga-1 (ok701) loss of function
mean lifespan increased 26.1% (significant)
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