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Observation 97

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Species Caenorhabditis elegans
Strain Bristol N2
Lifespan
Reference Lifespan
Lifespan Change
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Arantes-Oliveira N, Apfeld J, Dillin A, Kenyon C. (2002). Regulation of life-span by germ-line stem cells in Caenorhabditis elegans.. Science 295: 502-5. [pubmed]
Details

mes-1(bn7) animals that lack germ cells have a life-span that is extended by approximately 60% compared to mes-1(bn7) animals that are fertile.

Other phenotypes: This life-span extension requires daf-16. Homozygous mes-1 mutant progeny from homozygous mutant mothers are sterile [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
mes-1 non-null recessive 181362 View