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Observation 83

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Species Saccharomyces cerevisiae
Strain BKY1-14c
Mating Type matalpha
Temperature 30
Lifespan 17 divisions
Reference Lifespan 19 divisions
Lifespan Change -10.53%
Lifespan Measure median
Lifespan Effect decreased
Significance significant
Citation Kennedy BK, Austriaco NR, Zhang J, Guarente L. (1995). Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae.. Cell 80: 485-96. [pubmed]
Details
Deletion of SIR4 does not extend life span.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
SIR4 deletion / null