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Observation 76

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Species Caenorhabditis elegans
Strain Bristol N2
Lifespan
Reference Lifespan
Lifespan Change
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Kawano T, Ito Y, Ishiguro M, Takuwa K, Nakajima T, Kimura Y. (2000). Molecular cloning and characterization of a new insulin/IGF-like peptide of the nematode Caenorhabditis elegans.. Biochem. Biophys. Res. Commun. 273: 431-6. [pubmed]
Details

RNAi mutants display an increased life span of around 30-40%.

Other phenotypes: RNAi animals are slow growing but do not display any dauer phenotypes.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
Ceinsulin-1 RNAi knockdown