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Observation 734

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Species Drosophila melanogaster
Strain
Lifespan
Reference Lifespan
Lifespan Change 20%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation . (2005). Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly.. Cell Metab. 1: 145-52. [pubmed]
Details

Overexpression of human UCP2 in the fly nervous system extended lifespan by 10-30%.

Other phenotypes: Ubiquitous overexpression was lethal.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
UCP2 over-expression