Sageweb.org > Tools

Observation 727

Export: CSV XML YAML
User Comments

Please login to leave comments.

Species Drosophila melanogaster
Strain
Lifespan
Reference Lifespan
Lifespan Change 15%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Umeda-Kameyama Y, Tsuda M, Ohkura C, Matsuo T, Namba Y, Ohuchi Y, Aigaki T. (2007). Thioredoxin suppresses Parkin-associated endothelin receptor-like receptor-induced neurotoxicity and extends longevity in Drosop. J. Biol. Chem. 282: 11180-7. [pubmed]
Details

Overexpression in neurons extended the mean lifespan by 15%.

Other phenotypes: Overexpression increased the level of locomotor activity in aged flies.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
TrxT over-expression 31443 View