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Observation 70

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Species Caenorhabditis elegans
Strain N2
Sex hermaphrodite
Temperature 20
Lifespan
Reference Lifespan
Lifespan Change
Lifespan Measure mean
Lifespan Effect none
Significance
Citation Lakowski B, Hekimi S. (1998). The genetics of caloric restriction in Caenorhabditis elegans.. Proc. Natl. Acad. Sci. U.S.A. 95: 13091-6. [pubmed]
Details

The effect of mutations in 15 unc genes on life span was examined with mutations in 14 of these genes (unc-1, -4, -6, -7, -9, -24, -25, -29, -30, -46, -47, -49, -79, and -80) failing to lengthen life span.

Other phenotypes: Life span of unc-4(e120) males is extended relative to hermaphrodites approximately 2-fold [pubmed]. Mutants are uncoordinated [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
unc-4 unknown 174544 View