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Observation 640

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Species Mus musculus
Strain
Lifespan
Reference Lifespan
Lifespan Change 20%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Miskin R, Masos T, Yahav S, Shinder D, Globerson A. (0). AlphaMUPA mice: a transgenic model for increased life span.. Neurobiol. Aging 20: 555-64. [pubmed]
Details

Overexpression in the brain of transgenic mice resulted in a prolonged lifespan (20%).

Other phenotypes: Also in less food consumption (20%), reduced body weight (20%) and reduced temperature.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
Plau over-expression 18792 View