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Observation 555

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Species Mus musculus
Strain
Lifespan
Reference Lifespan
Lifespan Change 23%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Li Q, Ren J. (2007). Influence of cardiac-specific overexpression of insulin-like growth factor 1 on lifespan and aging-associated changes in cardiac. Aging Cell 6: 799-806. [pubmed]
Details

Cardiac specific overexpression results in a 23% increase in median lifespan.

Other phenotypes: No increase in maximum lifespan.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
Igf1 over-expression 16000 View