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Observation 5187

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Species Caenorhabditis elegans
Strain N2
Sex hermaphrodite
Temperature 25
Lifespan 15 days
Reference Lifespan 15 days
Lifespan Change
Lifespan Measure median
Lifespan Effect decreased
Significance significant
Citation Zhang T, Hwang HY, Hao H, Talbot C, Wang J. (2012). Caenorhabditis elegans RNA-processing Protein TDP-1 Regulates Protein Homeostasis and Lifespan. :. [pubmed]
Details
Mutation of tdp-1 requires daf-16 to extend life span.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
daf-16 mu86 loss of function