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Observation 5185

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Species Caenorhabditis elegans
Strain N2
Sex hermaphrodite
Temperature 25
Lifespan 15 days
Reference Lifespan 15 days
Lifespan Change
Lifespan Measure median
Lifespan Effect increased
Significance significant
Citation Zhang T, Hwang HY, Hao H, Talbot C, Wang J. (2012). Caenorhabditis elegans RNA-processing Protein TDP-1 Regulates Protein Homeostasis and Lifespan. :. [pubmed]
Details
Mutation of tdp-1 extends life span independently of hsf-1.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
tdp-1 ok781 unknown
hsf-1 sy441 normal