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Observation 5110

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Species Caenorhabditis elegans
Strain daf-2(e1370)
Temperature 20
Lifespan 54 days
Reference Lifespan 67 days
Lifespan Change -19.4%
Lifespan Measure max
Lifespan Effect decreased
Significance significant
Citation Yang W, Hekimi S. (2010). A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biol. [pubmed]
Details
Treatment of 10 mM NAC (N-acetyl-cysteine) had shortened maximum lifespan of daf-2(e1370) mutant worms by approximately 20% relative to mutant lifespan under normal conditions.

Compound Interventions

Name Quantity Ncbi Id
NAC 10 mM