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Observation 511

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Species Drosophila melanogaster
Strain
Lifespan
Reference Lifespan
Lifespan Change 24%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Orr WC, Radyuk SN, Prabhudesai L, Toroser D, Benes JJ, Luchak JM, Mockett RJ, Rebrin I, Hubbard JG, Sohal RS. (2005). Overexpression of glutamate-cysteine ligase extends life span in Drosophila melanogaster.. J. Biol. Chem. 280: 37331-8. [pubmed]
Details

Overexpression extended the mean lifespan by up to 24%.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
Gclm over-expression 248194 View