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Observation 5108

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Species Caenorhabditis elegans
Strain isp-1(qm150)
Temperature 20
Lifespan 38 days
Reference Lifespan 53 days
Lifespan Change -28.3%
Lifespan Measure max
Lifespan Effect decreased
Significance significant
Citation Yang W, Hekimi S. (2010). A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biol. [pubmed]
Details
Treatment of 10 mM NAC (N-acetyl-cysteine) had shortened maximum lifespan of isp-1(qm150) mutant worms by approximately 28% relative to mutant lifespan under normal conditions.

Compound Interventions

Name Quantity Ncbi Id
NAC 10 mM