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Observation 5101

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Species Caenorhabditis elegans
Strain nuo-6(qm200)
Temperature 20
Lifespan 20.7 days
Reference Lifespan 33.4 days
Lifespan Change -38.02%
Lifespan Measure mean
Lifespan Effect decreased
Significance significant
Citation Yang W, Hekimi S. (2010). A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biol. [pubmed]
Details
Treatment of N2 worms with N-acetyl-cysteine had no significant effect on lifespan. NAC treatment fully abolished the increased longevity of nuo-6, decreasing lifespan 35% to that of N2 control.

Compound Interventions

Name Quantity Ncbi Id
NAC 10 mM