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Observation 510

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Species Drosophila melanogaster
Strain
Lifespan
Reference Lifespan
Lifespan Change 50%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Orr WC, Radyuk SN, Prabhudesai L, Toroser D, Benes JJ, Luchak JM, Mockett RJ, Rebrin I, Hubbard JG, Sohal RS. (2005). Overexpression of glutamate-cysteine ligase extends life span in Drosophila melanogaster.. J. Biol. Chem. 280: 37331-8. [pubmed]
Details

Overexpression extended mean and maximum lifespan by up to 50%.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
Gclc over-expression 53581 View