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Observation 5092

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Species Caenorhabditis elegans
Strain mev-1(kn1)
Temperature 20
Lifespan 16 days
Reference Lifespan 16 days
Lifespan Change
Lifespan Measure mean
Lifespan Effect increased
Significance significant
Citation Cheong MC, Na K, Kim H, Jeong SK, Joo HJ, Chitwood DJ, Paik YK. (2011). A potential biochemical mechanism underlying the influence of sterol deprivation stress on Caenorhabditis elegans longevity. J. Biol. Chem. [pubmed]
Treatment of mev-1(kn1) mutant worms with 25 µM Aza in the presence of 5 µg/ml of sitosterol had no significant effect on MLS compared with those grown in the presence of sitosterol alone.

Compound Interventions

Name Quantity Ncbi Id
25-azacoprostane 25 µM