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Observation 5041

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Species Caenorhabditis elegans
Strain CRH-1 NULL
Temperature 20
Lifespan 18 days
Reference Lifespan 18 days
Lifespan Change
Lifespan Measure median
Lifespan Effect decreased
Significance significant
Citation Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A. (2011). Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature 470: 404-8. [pubmed]
Details
RNAi of crtc-1 has no significant effect on lifespan of crh-1 (nn3315) nulls.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
crtc-1 RNAi knockdown