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Observation 5027

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Species Caenorhabditis elegans
Strain N2
Temperature 20
Lifespan 26 days
Reference Lifespan 26 days
Lifespan Change
Lifespan Measure max
Lifespan Effect increased
Significance significant
Citation Fierro-González JC, González-Barrios M, Miranda-Vizuete A, Swoboda P. (2011). The thioredoxin TRX-1 regulates adult lifespan extension induced by dietary restriction in Caenorhabditis elegans. Biochem. Biophys. Res. Commun. [pubmed]
Maximum lifespan of trx-1(ok1449);osm-5(p813) double mutant was not significantly different than N2 control.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
trx-1 ok1449 loss of function
osm-5 p813 loss of function