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Observation 4702

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Species Mus musculus
Strain Line A2
Sex female
Lifespan 26
Reference Lifespan 26
Lifespan Change
Lifespan Measure mean
Lifespan Effect decreased
Significance significant
Citation Chiba T, Kamei Y, Shimizu T, Shirasawa T, Katsumata A, Shiraishi L, Sugita S, Ogawa Y, Miura S, Ezaki O. (2009). Overexpression of FOXO1 in skeletal muscle does not alter longevity in mice. Mech. Ageing Dev. [pubmed]
Details
There was no significant difference in survival between FOXO1 mice and wild-type littermates, for both males and females.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
Fox01 over-expression