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Observation 4578

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Species Caenorhabditis elegans
Strain fem-1(hc17);eat-2(ad465)
Lifespan 32 days
Reference Lifespan 32 days
Lifespan Change
Lifespan Measure mean
Lifespan Effect increased
Significance significant
Citation Lee GD, Wilson MA, Zhu M, Wolkow CA, de Cabo R, Ingram DK, Zou S. (2006). Dietary deprivation extends lifespan in Caenorhabditis elegans. Aging Cell 5: 515-24. [pubmed]
DD did not lengthen mean or maximum lifespan in slow-feeding fem-1(hc17); eat-2(ad465) worms, which are subject to DR, although DD significantly increased both mean and maximum lifespan in the fem-1(hc17) single mutant by 28.8% (P < 0.0001) and 25.2% (P < 0.01), respectively.

Environment Interventions

Type Body
dietary deprivation Adult worms transferred to plates without food.