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Observation 4547

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Species Caenorhabditis elegans
Strain N2
Temperature 20
Lifespan 20
Reference Lifespan 20
Lifespan Change
Lifespan Measure mean
Lifespan Effect increased
Significance significant
Citation Curtis R, O'Connor G, DiStefano PS. (2006). Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. Aging Cell 5: 119-26. [pubmed]
There was no significant difference in mean lifespan of double mutant clk-1(qm30); aak-2(ok524) relative to N2 lifespan.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
clk-1 qm30 loss of function
aak-2 ok524 loss of function