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Observation 448

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Species Drosophila melanogaster
Strain
Lifespan
Reference Lifespan
Lifespan Change 30%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Shepherd JC, Walldorf U, Hug P, Gehring WJ. (1989). Fruit flies with additional expression of the elongation factor EF-1 alpha live longer.. Proc. Natl. Acad. Sci. U.S.A. 86: 7520-1. [pubmed]
Details

Overexpression results in lifespan extension by 18%-41%.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
Ef1alpha48D over-expression 36271 View