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Observation 44

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Species Caenorhabditis elegans
Strain N2
Sex hermaphrodite
Temperature 25.5
Lifespan 21.7 days
Reference Lifespan 17.2 days
Lifespan Change 26.16%
Lifespan Measure mean
Lifespan Effect increased
Significance significant
Citation Cypser JR, Johnson TE. (0). The spe-10 mutant has longer life and increased stress resistance.. Neurobiol. Aging 20: 503-12. [pubmed]

The spe-10 mutation significantly increased mean life span. Additionally, the mutation significantly increased resistance to both UV light and to heat. Resistance to paraquat was not significantly different from that of wild-type, nor were any dauers formed at 27 degrees C. No significant correlation was found between the UV resistance and the fertility defect, nor was the UV resistance attributable to a hormetic effect.

This experiment was performed in liquid medium

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
spe-10 hc104 unknown 3565514 View