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Observation 4383

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Species Schizosaccharomyces pombe
Strain
Lifespan
Reference Lifespan
Lifespan Change 300%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Roux AE, Quissac A, Chartrand P, Ferbeyre G, Rokeach LA. (2006). Regulation of chronological aging in Schizosaccharomyces pombe by the protein kinases Pka1 and Sck2. Aging Cell 5: 345-57. [pubmed]
Details
Knockouts exhibited a three-fold increase in lifespan.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
Pka1 loss of function