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Observation 435

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Species Drosophila melanogaster
Strain DJ-1α
Lifespan 17
Reference Lifespan 38
Lifespan Change -55.26%
Lifespan Measure
Lifespan Effect decreased
Significance significant
Citation Lavara-Culebras E, Paricio N. (2007). Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits. Gene 400: 158-65. [pubmed]
Details
RNA interference shortened mean lifespan 55%/

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
DJ-1alpha RNAi knockdown 36543 View