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Observation 3798

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Species Caenorhabditis elegans
Strain N2
Sex hermaphrodite
Temperature 25
Lifespan 77 days
Reference Lifespan 21 days
Lifespan Change 266.67%
Lifespan Measure max
Lifespan Effect increased
Significance significant
Citation Meissner B, Boll M, Daniel H, Baumeister R. (2004). Deletion of the intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans. J. Biol. Chem. [pubmed]
Details
Double mutation extended maximum lifespan 266%.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
pep-2 lg601 deletion / null
daf-2 e1370 loss of function