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Observation 348

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Species Drosophila melanogaster
Strain
Lifespan
Reference Lifespan
Lifespan Change 42%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Finley KD, Edeen PT, Cumming RC, Mardahl-Dumesnil MD, Taylor BJ, Rodriguez MH, Hwang CE, Benedetti M, McKeown M. (2003). blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration.. J. Neurosci. 23: 1254-64. [pubmed]
Details

Mean lifespan is decreased 40-45% in bchs mutant adults.

Other phenotypes: No pronounced developmental defects were observed and young adults have normal behaviors, indicating that the bchs gene is essential for normal adult survival and longevity.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
bchs deletion / null 33819 View