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Observation 334

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Species Drosophila melanogaster
Strain
Lifespan
Reference Lifespan
Lifespan Change 33%
Lifespan Measure
Lifespan Effect increased
Significance significant
Citation Juh√°sz G, Erdi B, Sass M, Neufeld TP. (2007). Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Droso. Genes Dev. [pubmed]
Details

Knockouts are short-lived by 33%.

Other phenotypes: Knockouts are also hypersensitive to nutrient and oxidative stress

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
Atg7 deletion / null 37141 View