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Observation 32

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Species Saccharomyces cerevisiae
Strain YB332
Mating Type mata
Temperature 30
Lifespan 14.5 divisions
Reference Lifespan 27.5 divisions
Lifespan Change -47.27%
Lifespan Measure mean
Lifespan Effect decreased
Significance significant
Citation Ashrafi K, Lin SS, Manchester JK, Gordon JI. (2000). Sip2p and its partner snf1p kinase affect aging in S. cerevisiae.. Genes Dev. 14: 1872-85. [pubmed]
Details
The temperature-sensitive Nmt1-451D allele shortens life span at the permissive temperature.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
NMT1 451D loss of function