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Observation 2439

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Species Caenorhabditis elegans
Strain N2
Sex hermaphrodite
Temperature 20
Lifespan 72.8 days
Reference Lifespan 18.4 days
Lifespan Change 295.65%
Lifespan Measure mean
Lifespan Effect increased
Significance significant
Citation Apfeld J, Kenyon C. (1999). Regulation of lifespan by sensory perception in Caenorhabditis elegans.. Nature 402: 804-9. [pubmed]
Details
Several (but not all) mutations that cause defects in sensory cilia or their support cells, or in sensory signal transduction, extend lifespan. These mutations do not further extend long-lived daf-2 mutants

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
osm-5 p813 unknown

Environment Interventions

Type Body
Somatic gonad ablation Z1, Z4 laser ablation at L1 larval stage