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Observation 21

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Species Saccharomyces cerevisiae
Strain W303-1A
Temperature 30
Lifespan 15.9 divisions
Reference Lifespan 20.6 divisions
Lifespan Change -22.82%
Lifespan Measure mean
Lifespan Effect decreased
Significance significant
Citation McVey M, Kaeberlein M, Tissenbaum HA, Guarente L. (2001). The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arres. Genetics 157: 1531-42. [pubmed]
Deletion of RAD9 suppresses the arrest phenotype of sgs1, srs2, and sgs1 srs2 cells but does not promote their longevity.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
RAD9 deletion / null 851803 View