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Observation 2050

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Species Podospora anserina
Strain
Lifespan
Reference Lifespan
Lifespan Change 400%
Lifespan Measure mean
Lifespan Effect increased
Significance significant
Citation Sellem CH, Marsy S, Boivin A, Lemaire C, Sainsard-Chanet A. (2007). A mutation in the gene encoding cytochrome c1 leads to a decreased ROS content and to a long-lived phenotype in the filamentous fungus Podospora anserina. Fungal Genet. Biol. [pubmed]
Details
Mutants live longer by more than 400%. Mutants have a reduced growth rate, a reduced reactive oxygen species production.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
cyc1 loss of function