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Observation 1929

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Species Mus musculus
Strain
Sex male
Lifespan 28.9
Reference Lifespan 23.7
Lifespan Change 21.94%
Lifespan Measure mean
Lifespan Effect increased
Significance significant
Citation Chiu CH, Lin WD, Huang SY, Lee YH. (2004). Effect of a C/EBP gene replacement on mitochondrial biogenesis in fat cells.. Genes Dev. 18: 1970-5. [pubmed]
Details
Replacing the CEBPA gene by CEBPB increased lifespan by about 20%.

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
CEBPA deletion / null
CEBPB over-expression