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Observation 19

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Species Saccharomyces cerevisiae
Strain PSY316
Mating Type matalpha
Temperature 30
Lifespan 22.1 divisions
Reference Lifespan 22 divisions
Lifespan Change 0.45%
Lifespan Measure mean
Lifespan Effect increased
Significance not significant
Citation Park PU, Defossez PA, Guarente L. (1999). Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae.. Mol. Cell. Biol. 19: 3848-56. [pubmed]

Deletion has no effect on life span in PSY316.

Other phenotypes: Mutation results in decreased repair of the non-transcribed strand in rDNA [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
RAD7 deletion / null 853512 View