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Observation 16

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Species Saccharomyces cerevisiae
Strain PSY316
Mating Type matalpha
Temperature 30
Lifespan 21.1 divisions
Reference Lifespan 22 divisions
Lifespan Change -4.09%
Lifespan Measure mean
Lifespan Effect decreased
Significance not significant
Citation Park PU, Defossez PA, Guarente L. (1999). Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae.. Mol. Cell. Biol. 19: 3848-56. [pubmed]

Deletion has no effect on life span in PSY316.

Other phenotypes: Mutant is defective for transcription-coupled repair but shows no defect in global genome repiar [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
RAD26 deletion / null 853492 View