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Observation 158

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Species Saccharomyces cerevisiae
Strain SP-1
Lifespan
Reference Lifespan
Lifespan Change
Lifespan Measure
Lifespan Effect decreased
Significance significant
Citation Fabrizio P, Liou LL, Moy VN, Diaspro A, Valentine JS, Gralla EB, Longo VD. (2003). SOD2 functions downstream of Sch9 to extend longevity in yeast.. Genetics 163: 35-46. [pubmed]
Details

Deletion of RAS1 slightly shortened stationary phase survival.

Other phenotypes: Deletion of RAS1 results in a 23% increase in mean and 29% increase in maximum replicative life-span [pubmed]. Overexpression of RAS1 has no effect on replicative life-span [pubmed].

Gene Interventions:

Symbol Allele Allele Type NCBI Gene ID More
RAS1 deletion / null 854268 View